ArticleFish physiology and biochemistry2025
Exposure to bisphenol S induces organ toxicity by disrupting oxidative and antioxidant defense system and blood physiology in Labeo rohita (Hamilton, 1822).
Article in Fish physiology and biochemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Mutual Influence of Sucralose and Bisphenol A on Biological and Neurobehavioral Action inInternational journal of molecular sciences · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bisphenol S is an emerging pollutant that is contaminating aquatic ecosystems and causing detrimental effects on aquatic organisms, especially fish. Therefore, the study was designed to evaluate the toxicity of bisphenol S (BPS) through genotoxic, biochemical, histopathological, and oxidative damage in the liver, gills, and kidneys of Labeo rohita fish. Fish were exposed to three different concentrations (400 µg/L, 800 µg/L, and 1000 µg/L) of BPS for 21 days. A significant (p ≤ 0.05) decline in antioxidant enzymatic activity of superoxide dismutase (SOD), catalase (CAT), reduced glutathione (GSH), and peroxidase (POD) was observed in all tissues, whereas elevation in oxidative contents (TBARS and ROS) was observed. Comet analysis showed elevated olive tail moment and % of DNA damage. Light microscopy revealed several anomalies including cluster nuclei formation, damaged parenchyma cells, sinusoidal spaces, and melanomacrophage in the kidney, sinusoidal spaces, dilated hepatic vein, pyknotic nuclei, melanomacrophage, and cell necrosis in the liver and bone cell deformities, lamellar aneurysm, hyperplasia, and curved secondary gill lamellae in gills. Results of hematobiochemical analysis revealed a significant (p ≤ 0.05) increment in hematocrit, WBCs, cholesterol, blood glucose, triglycerides, AST, ALT, T
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39982559What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.