Evidence map›Paper›PMID 39982515›Full record

Observational studyClinical oral investigations2025

Tissue autofluorescence system as an aid for Dental Hygienist to screening oral mucosa alterations during supportive periodontal care. An observational single-arm study.

Alessandro Cuozzo, Andrea Blasi, Federica Canfora, Vincenzo Iorio-Siciliano, Loredana Bellia, Luca Ramaglia

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alessandro CuozzoDepartment of Periodontology, School of Dental Medicine, University of Naples Federico II, Via S. Pansini 5, 80131, Naples, Italy.
Andrea BlasiDepartment of Periodontology, School of Dental Medicine, University of Naples Federico II, Via S. Pansini 5, 80131, Naples, Italy.
Federica CanforaDepartment of Oral Medicine, School of Dental Medicine, University of Naples Federico II, Via S. Pansini 5, 80131, Naples, Italy.
Vincenzo Iorio-SicilianoDepartment of Periodontology, School of Dental Medicine, University of Naples Federico II, Via S. Pansini 5, 80131, Naples, Italy. enzois@libero.it.
Loredana BelliaDepartment of Periodontology, School of Dental Medicine, University of Naples Federico II, Via S. Pansini 5, 80131, Naples, Italy.
Luca RamagliaDepartment of Periodontology, School of Dental Medicine, University of Naples Federico II, Via S. Pansini 5, 80131, Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate a tissue autofluorescence (AF) system as an aid for Dental Hygienist (DH) to screening oral mucosa alterations during supportive periodontal care (SPC). MATERIALS AND

methodsTwo hundred patients in regular SPC with no previous oral mucosa lesions were enrolled. The oral cavity of each patient was examined by a DH without and with the AF system. Afterward, the patient was examined by a General Dentist (GD) by means of conventional visual inspection alone. The primary outcome was the sensitivity of AF system used by a DH. Furthermore, the specificity, predictive values and likelihood ratios were also evaluated. Receiver operating characteristic (ROC) curves were generated and area under ROC (AUROC) was estimated to overall evaluate the ability of DH to detect oral mucosa lesions with and without an AF system.

resultsAfter completion of intraoral screening, 111 and 66 oral mucosa alterations were detected by DH without and with the AF system. A total of 83 lesions were instead recorded by GD with conventional inspection. The sensitivity and specificity of AF system used by a DH were 61.5% and 90.6% while the conventional visual inspection showed a sensitivity of 81.3% and specificity of 97.6%. AUROC values of 0.760 and 0.894 were found for AF system and for conventional visual inspection respectively.

conclusionsWhitin the limitations of present study, the results showed for DH an increase of specificity and a loss of sensitivity in detection of oral mucosa alterations using the AF system. CLINICAL RELEVANCE: The use of AF system may be considered an aid for DH to improve screening of oral mucosal alterations during SPC.

Indexed as

Dental HygienistsMouth MucosaOptical ImagingPeriodontal DiseasesAdultAgedFemaleHumansMaleMiddle AgedSensitivity and SpecificityAutofluorescenceEarly diagnosisInflammationOral mucosal lesionSupportive periodontal care

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.