ArticleEuropean journal of trauma and emergency surgery : official publication of the European Trauma Society2025
A high rate of mortality in liver cirrhosis patients after emergency abdominal surgery.
Article in European journal of trauma and emergency surgery : official publication of the European Trauma Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Impairment in activities of daily living and textbook outcome after major emergency abdominal surgery.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
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Abstract
purposeIn the elective setting, there are high mortality rates for patients with liver cirrhosis after surgery. Few studies focus on emergency surgery. This study investigates mortality and morbidity of patients with cirrhosis undergoing emergency abdominal surgery.
methodsIn a database established at two Copenhagen University Hospitals (Herlev and North Zealand), including all patients operated in an emergency setting (n = 1116), including all patients with known cirrhosis at time of surgery. Postoperative complications, and mortality rates were evaluated by a matched case-control method, matching cases and controls according to surgical procedure, age, sex and American Society of Anaesthesiologists-class (ASA). Medical and surgical complications were classified according to the Clavien-Dindo classification.
resultsIn the study, 24 patients with cirrhosis and 48 matched controls were evaluated. The 30-day mortality was 37.5% for patients with cirrhosis and 12.5% for controls (OR 4.2, 95% CI [1.28, 13.80], p = 0.014) and 90-day mortality was 62.5% for patients with cirrhosis compared to 18.8% for controls (OR 7.22, 95% CI [2.41, 21.68], p < 0.001). For patients with cirrhosis 58.3% had surgical complications compared to 31.3% for the controls (p = 0.027). The reoperation rate was 45.8% in the cirrhosis group and 22.9% in the control group (p = 0.047). The days-alive-out-of-hospital at 90-days (DAOH-90) was 9 days in the cirrhosis group and 78 days in the control group (p < 0.001).
conclusionThis retrospective study shows that patients with cirrhosis have significantly higher mortality rates after emergency surgery, more surgical complications and reoperations, and reduced DAOH-90.
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