Evidence map›Paper›PMID 39982264›Full record

ArticleNeuroSci2025

Stress-Induced Hyperglycemia Predicts Poor Outcomes in Primary Intracerebral Hemorrhage Patients.

Kevin Gilotra, Jade Basem, Melissa Janssen, Sujith Swarna, Racheed Mani, Benny Ren, Reza Dashti

Abstract read
In one paragraph

Article in NeuroSci, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kevin GilotraRenaissance School of Medicine at Stony Brook University, Stony Brook, NY 11794, USA.ORCID 0000-0001-6407-0022
Jade BasemRenaissance School of Medicine at Stony Brook University, Stony Brook, NY 11794, USA.ORCID 0000-0002-7506-547X
Melissa JanssenDepartment of Neurosurgery, Loma Linda University, Loma Linda, CA 92345, USA.
Sujith SwarnaRenaissance School of Medicine at Stony Brook University, Stony Brook, NY 11794, USA.ORCID 0000-0003-4222-3408
Racheed ManiDepartment of Neurology, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY 11794, USA.ORCID 0000-0003-0927-4924
Benny RenBiostatistical Consulting Core, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY 11794, USA.
Reza DashtiDepartment of Neurosurgery, Renaissance School of Medicine at Stony Brook University, Stony Brook, NY 11794, USA.ORCID 0000-0002-2257-262X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe current literature suggests hyperglycemia can predict poor outcomes in patients with primary intracerebral hemorrhage (ICH). Chronic hyperglycemia is seen in patients with pre-existing diabetes (DM); however, acute hyperglycemia in non-diabetic patients is defined as stress-induced hyperglycemia (SIH). This study explored the influence of hyperglycemia on outcomes of primary ICH patients both in the presence and absence of pre-existing DM.

methodsData regarding admission glucose, pre-existing DM, inpatient mortality, and modified Rankin Scale (mRS) scores at discharge were available for 636 patients admitted to Stony Brook Hospital from January 2011 to December 2022 with a primary diagnosis of ICH. Regression models were used to compare outcomes between patients with admission hyperglycemia and/or pre-existing DM to a control group of normoglycemic and non-diabetic ICH patients.

resultsPatients with SIH had higher inpatient mortality rates and worse mRS scores at discharge (

conclusionsOur findings suggest that SIH may play a greater role in predicting poor outcomes at discharge rather than a history of poorly controlled DM with chronic hyperglycemia. To develop a more thorough understanding of this topic, prospective studies evaluating the effect of changes in serum glucose during hospital stay on short and long-term outcomes is needed.

Indexed as

diabeteshyperglycemiaintracerebral hemorrhageoutcomeprimarystress

Identifiers

PMID39982264
PMCPMC11843840

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.