Evidence map›Paper›PMID 39982244›Full record

ArticleMedical sciences (Basel, Switzerland)2025

Outcomes in Acute Decompensated Congestive Heart Failure Admissions with Chronic Liver Disease: A Nationwide Analysis Using the National Inpatient Sample.

Vivek Joseph Varughese, Vignesh Krishnan Nagesh, Pratiksha Moliya, Nelson Gonzalez, Emelyn Martinez, Hata Mujadzic, Maggie James, Abraham Lo, Simcha Weissman

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Medical sciences (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Vivek Joseph VarugheseDepartment of Internal Medicine, University of South Carolina, Easley, SC 29640, USA.
Vignesh Krishnan NageshDepartment of Internal Medicine, Hackensack Palisades Medical Center, North Bergen, NJ 07047, USA.
Pratiksha MoliyaDepartment of Gastroenterology and Hepatology, University of Nebraska, Omaha, NE 68001, USA.
Nelson GonzalezDepartment of Internal Medicine, University of South Carolina, Easley, SC 29640, USA.
Emelyn MartinezDepartment of Internal Medicine, Hackensack Palisades Medical Center, North Bergen, NJ 07047, USA.
Hata MujadzicDepartment of Internal Medicine, University of South Carolina, Easley, SC 29640, USA.
Maggie JamesDepartment of Internal Medicine, Hackensack Palisades Medical Center, North Bergen, NJ 07047, USA.
Abraham LoDepartment of Internal Medicine, Hackensack Palisades Medical Center, North Bergen, NJ 07047, USA.
Simcha WeissmanDepartment of Internal Medicine, Hackensack Palisades Medical Center, North Bergen, NJ 07047, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe aim of our study was primarily to analyze hospital outcomes for acute decompensated heart failure (ADHF) admissions with a comorbid diagnosis of chronic liver disease (CLD).

methodsThe NIS was used to select ADHF admissions. The population characteristics of general ADHF admissions were compared with ADHF admissions with a comorbid diagnosis of CLD. Multivariate probit logistic regression was used to analyze the association between a documented diagnosis of CLD/alcoholic liver disease and all-cause mortality in ADHF admissions. Confounders were accounted for. Propensity scoring and nearest neighbor matching were conducted to select a matched cohort with and without CLD from ADHF admissions to further look at mortality outcomes.

resultsADHF admissions with a comorbid diagnosis of CLD had a significantly higher proportion of all-cause mortality, 0.054 (0.053-0.057), a higher length of hospital stay, 6.95 days (6.84-7.06), and a higher mean of total hospital charges, USD 88,068.1, when compared to ADHF admissions without a comorbid diagnosis of CLD: all-cause mortality, 0.045 (0.044-0.046); length of hospital stay, 6.18 days (6.13-6.23); and mean total hospital charges, USD 79,946.21. A comorbid diagnosis of CLD had a significant association with all-cause mortality in ADHF admissions: OR 1.23 (1.17-1.29) after accounting for confounders. In the propensity-matched cohorts, the cohort with a diagnosis of CLD from the ADHF admissions had a higher proportion of all-cause mortality, 0.042 (0.036-0.049), when compared to the cohort without a diagnosis of chronic liver disease, 0.027 (0.022-0.033).

conclusionsIn analyzing the mortality and healthcare utilization outcomes for ADHF admissions, the comorbid diagnosis of CLD is shown to have significantly higher all-cause mortality, higher length of hospital stay, and higher mean total charges when compared to ADHF admissions without a diagnosis of CLD. A documented diagnosis of CLD had a statistically significant association with all-cause mortality in ADHF admissions after accounting for confounding factors.

Indexed as

Heart FailureLiver DiseasesAcute DiseaseAgedAged, 80 and overChronic DiseaseComorbidityFemaleHospitalizationHospital MortalityHumansInpatientsLength of StayMaleMiddle AgedUnited Stateschronic liver diseasecirrhosisheart failuremortalityNIS

Identifiers

PMID39982244
PMCPMC11843908

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.