Evidence map›Paper›PMID 39982232›Full record

ArticleAntibodies (Basel, Switzerland)2025

Investigation of Antibody Pharmacokinetics in Male Reproductive System and Its Characterization Using a Translational PBPK Model.

Sree Ojili, Dhaval K Shah

Abstract read
In one paragraph

Article in Antibodies (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sree OjiliDepartment of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, The State University of New York at Buffalo, Buffalo, NY 14214-8033, USA.
Dhaval K ShahDepartment of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, The State University of New York at Buffalo, Buffalo, NY 14214-8033, USA.ORCID 0000-0002-0723-6206

Funding

Enhancement of ADC selectivity by inverse targeting: Mechanistic studies and optimizationR01CA256928 · NCI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI BALTHASAR, JOSEPH P · 2021 to 2025
$1.8M
Pharmacokinetic strategies to increase monoclonal antibody uptake, distribution, and efficacy for treatment of solid tumorsR01CA246785 · NCI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI BALTHASAR, JOSEPH P, SHAH, DHAVAL K · 2020 to 2024
$1.8M
Pharmacokinetic / Pharmacodynamic Optimization of ADC Therapy for Acute Myeloid LeukemiaR01CA275967 · NCI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI Joseph P Balthasar, Dhaval K Shah · 2023 to 2026
$1.7M
Translational Systems Pharmacokinetic Models of Novel Anticancer BiologicsR01GM114179 · NIGMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI SHAH, DHAVAL K · 2015 to 2019
$1.7M
Proposal for Administrative supplement to Purchase NanoSight ProR01GM146097 · NIGMS · UNIVERSITY OF ALABAMA IN TUSCALOOSA · PI Ravikumar N Majeti, Dhaval K Shah · 2023 to 2026
$1.6M
Modulation of antigen pharmacokinetics with pH dependent antibodyR21AI138195 · NIAID · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI PARK, SHELDON · 2018 to 2019
$425k
center for protein therapeutics NANational Institute of Allergy and Infectious Diseases AI138195NCI NIH HHS R01 CA246785NCI NIH HHS R01CA246785, R01CA256928, and R01CA275967NCI NIH HHS R01 CA256928NCI NIH HHS R01 CA275967NIAID NIH HHS R21 AI138195NIGMS NIH HHS GM114179, GM146097NIGMS NIH HHS R01 GM114179NIGMS NIH HHS R01 GM146097
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

antibodyclinical translationmale reproductive systemPBPK modellingpharmacokinetics

Identifiers

PMID39982232
PMCPMC11843977

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.