Evidence map›Paper›PMID 39982226›Full record

ArticleAntibodies (Basel, Switzerland)2025

Purification of a Fc-Fusion Protein with [Bathophenathroline:metal] Complexes.

Thisara Jayawickrama Withanage, Ron Alcalay, Olga Krichevsky, Ellen Wachtel, Ohad Mazor, Guy Patchornik

Abstract read
In one paragraph

Article in Antibodies (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Thisara Jayawickrama WithanageDepartment of Chemical Sciences, Ariel University, Ariel 4070000, Israel.
Ron AlcalayIsrael Institute for Biological Research, Ness-Ziona 7410001, Israel.ORCID 0000-0003-1276-0464
Olga KrichevskyDepartment of Chemical Sciences, Ariel University, Ariel 4070000, Israel.
Ellen WachtelFaculty of Chemistry, Weizmann Institute of Science, Rehovot 7610001, Israel.
Ohad MazorIsrael Institute for Biological Research, Ness-Ziona 7410001, Israel.ORCID 0000-0001-5956-9865
Guy PatchornikDepartment of Chemical Sciences, Ariel University, Ariel 4070000, Israel.ORCID 0000-0002-6472-8354

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we assess an alternative Fc-fusion protein purification method that does not rely on chromatographic media or ligands. Recombinant human acetylcholinesterase, fused to the Fc domain of human IgG1 (henceforth, AChE-Fc), was purified with precipitated aromatic complexes composed of the bathophenanthroline (henceforth, batho) chelator with either Zn

Indexed as

acetylcholinesterasebathophenanthroline:Zn2+ complexesFc-fusion proteinsnon-chromatographic purification

Identifiers

PMID39982226
PMCPMC11843901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.