Evidence map›Paper›PMID 39982060›Full record

ArticlemSphere2025

Pariyamon Thaprawat, Fengrong Wang, Shreya Chalasani, Tracey L Schultz, Manlio Di Cristina, Vern B Carruthers

Abstract read
In one paragraph

Article in mSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pariyamon ThaprawatDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.ORCID 0000-0002-8058-1743
Fengrong WangDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Shreya ChalasaniDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Tracey L SchultzDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Manlio Di CristinaDepartment of Chemistry, Biology and Biotechnology, University of Perugia, Perugia, Umbria, Italy.ORCID 0000-0003-4154-5210
Vern B CarruthersDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, USA.ORCID 0000-0001-6859-8895

Funding

MICHIGAN MEDICAL SCIENTIST TRAINING PROGRAMT32GM007863 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI COLLINS, KATHLEEN L. · 1985 to 2024
$38.3M
Molecular Mechanisms of Microbial Pathogenesis Training ProgramT32AI007528 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CARRUTHERS, VERNON BRUCE · 1998 to 2024
$6.8M
Parasite autophagy as a key survival mechanism for the AIDS-associated pathogen Toxoplasma gondiiR01AI120607 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CARRUTHERS, VERNON BRUCE · 2016 to 2025
$4.0M
Identifying novel players in Toxoplasma autophagy during chronic infection”R21AI160610 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI CARRUTHERS, VERNON BRUCE · 2021 to 2022
$429k
Defining the role of TgATG9 in Toxoplasma gondii autophagy and persistenceF30AI169762 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI THAPRAWAT, PARIYAMON · 2022 to 2024
$82k
HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) F30I169762HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI120607HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) R01AI160610HHS | NIH | National Institute of Allergy and Infectious Diseases (NIAID) T32AI007528HHS | NIH | National Institute of General Medical Sciences (NIGMS) T32GM007863NIAID NIH HHS F30 AI169762NIAID NIH HHS R01 AI120607NIAID NIH HHS R21 AI160610NIAID NIH HHS T32 AI007528NIGMS NIH HHS T32 GM007863
6 · The paper itself

Abstract

Macroautophagy is an important cellular process involving lysosomal degradation of cytoplasmic components, facilitated by autophagy-related proteins. In the protozoan parasite IMPORTANCE: It is estimated that up to a third of the human population is chronically infected with

Indexed as

AutophagyPersistent InfectionProtozoan ProteinsToxoplasmaToxoplasmosisAnimalsFemaleMiceMice, Inbred C57BLProtozoan ProteinsautophagybradyzoitepersistanceToxoplasma gondii

Identifiers

PMID39982060
PMCPMC11934330

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.