Evidence map›Paper›PMID 39981914›Full record

ArticleOncology reports2025

Overexpression of FOS enhances the malignant potential of eutopic endometrial stromal cells in patients with endometriosis‑associated ovarian cancer.

Junyu Chen, Kang He, Xin Li, Mengqi Wang, Zhaoyun Yang, Zeyu Wang, Kai Wang, Weiqiang Jiang, Lijing Zhao, Manhua Cui

Abstract read
In one paragraph

Article in Oncology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Endometriosis: From Genes to Global Burden.International journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Junyu Chen *Department of Obstetrics and Gynecology, The Second Hospital of Jilin University, Changchun, Jilin 130041, P.R. China.
Kang He *Department of Rehabilitation, School of Nursing, Jilin University, Changchun, Jilin 130021, P.R. China.
Xin LiDepartment of Obstetrics and Gynecology, The Second Hospital of Jilin University, Changchun, Jilin 130041, P.R. China.
Mengqi WangDepartment of Obstetrics and Gynecology, The Second Hospital of Jilin University, Changchun, Jilin 130041, P.R. China.
Zhaoyun YangDepartment of Rehabilitation, School of Nursing, Jilin University, Changchun, Jilin 130021, P.R. China.
Zeyu WangDepartment of Rehabilitation, School of Nursing, Jilin University, Changchun, Jilin 130021, P.R. China.
Kai WangDepartment of Rehabilitation, School of Nursing, Jilin University, Changchun, Jilin 130021, P.R. China.
Weiqiang JiangDepartment of Rehabilitation, School of Nursing, Jilin University, Changchun, Jilin 130021, P.R. China.
Lijing ZhaoDepartment of Rehabilitation, School of Nursing, Jilin University, Changchun, Jilin 130021, P.R. China.
Manhua CuiDepartment of Obstetrics and Gynecology, The Second Hospital of Jilin University, Changchun, Jilin 130041, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometrial cysts of the ovary (EMC) may develop into endometriosis (EM)‑associated ovarian cancer over time (EAOC), but the pathogenesis of this disease has not been determined. In the present study, RNA sequencing was used to identify a feasible biomarker, and the molecular function of this biomarker in eutopic endometrial cells from EAOC and EMC patients was evaluated to explore the potential mechanism related to EAOC and orthotopic endometrial tissue. RNA sequencing was performed on 5 EAOC and 4 EMC tissue samples, and differential expression analysis was performed. To identify biomarkers, differentially expressed genes were subjected to protein‑protein interaction network design, Gene Ontology pathway enrichment, and Gene Set Enrichment Analysis pathway enrichment. The expression of

Indexed as

EndometriosisEndometriumOvarian NeoplasmsProto-Oncogene Proteins c-fosAdultBiomarkers, TumorCell MovementCell ProliferationFemaleGene Expression Regulation, NeoplasticHumansMiddle AgedProtein Interaction MapsStromal CellsUp-RegulationBiomarkers, TumorFOS protein, humanProto-Oncogene Proteins c-fosbiomarkerendometrial cyst of ovaryendometriosis‑associated ovarian cancerFOS

Identifiers

PMID39981914
PMCPMC11851058

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.