Evidence map›Paper›PMID 39981811›Full record

ArticleJournal of medical imaging and radiation oncology2025

Evaluation of the Efficacy and Safety of Transjugular Intrahepatic Portosystemic Shunt Combined With Concurrent Antegrade Embolization of Large Spontaneous Portosystemic Shunts.

Ze Wang, Xiao-Yang Xu, Chen-You Liu, Jin-Tao Huang, Wan-Ci Li, Shuai Zhang, Jian Shen, Bin-Yan Zhong, Xiao-Li Zhu

Abstract read
In one paragraph

Article in Journal of medical imaging and radiation oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Ze WangDepartment of Interventional Radiology, The First Affiliated Hospital of Soochow University, Suzhou, People's Republic of China.ORCID https://orcid.org/0009-0009-7821-7035
Xiao-Yang XuDepartment of Interventional Radiology, The First Affiliated Hospital of Soochow University, Suzhou, People's Republic of China.
Chen-You LiuDepartment of Interventional Radiology, The First Affiliated Hospital of Soochow University, Suzhou, People's Republic of China.
Jin-Tao HuangDepartment of Interventional Radiology, The First Affiliated Hospital of Soochow University, Suzhou, People's Republic of China.
Wan-Ci LiDepartment of Interventional Radiology, The First Affiliated Hospital of Soochow University, Suzhou, People's Republic of China.
Shuai ZhangDepartment of Interventional Radiology, The First Affiliated Hospital of Soochow University, Suzhou, People's Republic of China.
Jian ShenDepartment of Interventional Radiology, The First Affiliated Hospital of Soochow University, Suzhou, People's Republic of China.
Bin-Yan ZhongDepartment of Interventional Radiology, The First Affiliated Hospital of Soochow University, Suzhou, People's Republic of China.
Xiao-Li ZhuDepartment of Interventional Radiology, The First Affiliated Hospital of Soochow University, Suzhou, People's Republic of China.

Funding

2023 Soochow University-Hengrui Medical Horizontal Cooperation Translational Project H230578
6 · The paper itself

Abstract

objectivesTo compare the long-term efficacy and safety of transjugular intrahepatic portosystemic shunt (TIPS) combined with concurrent antegrade embolization in treating portal hypertension with oesophagogastric variceal bleeding in patients with and without large spontaneous portosystemic shunts (L-SPSSs). MATERIALS AND

methodsWe retrospectively analysed data from patients with portal hypertension who underwent TIPS from November 2015 to April 2022. The patients were screened according to the inclusion criteria and were divided into L-SPSSs group (L-S group) and Non L-SPSSs group (Non L-S group). The primary outcome was the 2-year liver transplantation-free survival (TFS) rate. Secondary outcomes contained the incidence of overt hepatic encephalopathy (OHE), ectopic embolization and the 2-year rebleeding rate.

resultsA total of 259 patients were enrolled (64 patients in L-S group and 195 patients in Non L-S group). The average age was 57.2 years, and the success rate of procedure was 100%. Baseline data showed no significant differences between two groups. There was a statistically significant difference in the 2-year liver transplantation-free rate between two groups (L-S vs. Non L-S, 84.38% vs. 71.28%; p = 0.045). OHE occurred in 19 (29.69%) patients with L-SPSSs and 104 (53.33%) patients without L-SPSSs, with a statistically significant difference (p = 0.001). And no statistically significant difference was found in ectopic embolism incidence rate and the 2-year rebleeding rate between two groups. Multivariate Cox regression analysis identified male gender, portal vein thrombosis and preoperative high blood ammonia levels as independent risk factors for long-term survival.

conclusionCompared to Non L-S group, the patients in L-S group achieve longer liver transplantation-free survival and lower incidence rate of OHE without increasing the risk of 2-year rebleeding and ectopic embolization.

Indexed as

Embolization, TherapeuticEsophageal and Gastric VaricesGastrointestinal HemorrhageHypertension, PortalPortasystemic Shunt, Transjugular IntrahepaticAdultAgedCombined Modality TherapyFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment Outcomelarge spontaneous portosystemic shuntsoesophagogastric variceal bleedingportal hypertensionTIPS

Identifiers

PMID39981811
PMCPMC11995249

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.