ArticleImmunity, inflammation and disease2025
Changes of Peripheral T Cells in Systemic Lupus Erythematosus Patients.
Article in Immunity, inflammation and disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Anti-CENP-B polarity divides SLE: divergent clinical-immune phenotypes and distinct treatment responses.Frontiers in immunology · 2026Article
- Combined assessment of 25(OH)D, CD4Frontiers in immunology · 2026Article
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Authors and funding
4 authors.
Funding
Abstract
backgroundEfficient indicators for evaluating the imbalance of lymphocyte function were crucial to clinical therapy in systemic lupus erythematosus (SLE) patients. This study aimed to find biomarkers to assess lymphocyte-mediated immune response in SLE patients.
methodsA total of 81 SLE patients (non-active: n = 35, active: n = 46) and 70 healthy donors were recruited in the study. Peripheral blood was obtained, and flow cytometry was used to detect circulating lymphocytes.
resultsData showed that the counts of CD3
conclusionThis study indicated that monitoring the alterations of circulating lymphocyte counts and surface molecules may be helpful to assess disease activity of SLE patients, even discriminate active and non-active patients, which was beneficial to choose the best treatment option in clinical therapy.
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