Evidence map›Paper›PMID 39981455›Full record

ArticleCureus2025

Development of Neuroblastoma During Growth Hormone Therapy for Short Stature in a Girl With Mosaic Turner Syndrome.

Takaya Honda, Katsuyuki Tanaka, Taiki Honma, Takuya Kamio, Masaharu Akiyama

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Takaya HondaPediatrics, The Jikei University School of Medicine, Tokyo, JPN.
Katsuyuki TanakaPediatrics, The Jikei University School of Medicine, Tokyo, JPN.
Taiki HonmaPediatrics, The Jikei University School of Medicine, Tokyo, JPN.
Takuya KamioPediatrics, The Jikei University School of Medicine, Tokyo, JPN.
Masaharu AkiyamaPediatrics, The Jikei University School of Medicine, Tokyo, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report the case of a girl with mosaic Turner syndrome who developed abdominal neuroblastoma during growth hormone (GH) therapy for short stature. The patient underwent chemotherapy for the unresectable tumor but died at the age of 10 years due to multiple metastases, five years and 10 months after the diagnosis of neuroblastoma. Although the risk of neuroblastoma does not increase in patients with Turner syndrome, the need for pre-treatment imaging studies for tumor screening remains controversial. However, our experience with this patient highlights the potential value of performing imaging studies both before and during GH treatment.

Indexed as

anaplastic lymphoma kinase genegrowth hormone therapyimaging studymosaic turner syndromeneuroblastoma

Identifiers

PMID39981455
PMCPMC11840272

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.