Evidence map›Paper›PMID 39981411›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2025

Ethical Issues in Uncontrolled Donation After Circulatory Determination of Death: A Scoping Review to Reveal Areas of Broad Consensus, and Those for Future Research.

Anastasia Georgiou, Weiyi Tan, Mihnea I Ionescu, Isla L Kuhn, Zoe Fritz

Abstract readScoping Review
In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Willing to Donate? A Quantitative and Thematic Analysis of Attitudes to Deceased Organ Donation in Different Circumstances.Health expectations : an international journal of public participation in health care and health policy · 2026
    Article
  4. A structured analysis of the concept of brain death.Theoretical medicine and bioethics · 2026
    Article
  5. Article
  6. Review
  7. Transplant International: Looking Back at 2025, Looking Forward to 2026.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  8. Article
  9. Implementation of a controlled DCD program in Western Austria - key considerations and insights.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  10. Article
  11. Review
  12. Article
  13. cDCDD and Heart Procurement: Challenges from a French Critical Care Perspective.Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Anastasia GeorgiouSchool of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
Weiyi TanSchool of Clinical Medicine, University of Cambridge, Cambridge, United Kingdom.
Mihnea I IonescuMiami Transplant Institute, Jackson Health System, Miami, FL, United States.
Isla L KuhnTHIS (The Healthcare Improvement Studies) Institute, University of Cambridge, Cambridge, United Kingdom.
Zoe FritzTHIS (The Healthcare Improvement Studies) Institute, University of Cambridge, Cambridge, United Kingdom.

Funding

Wellcome TrustWellcome Trust 208213/Z/17/Z
6 · The paper itself

Abstract

Uncontrolled donation after circulatory determination of death (uDCD) protocols are established in several countries with good outcomes. We reviewed the literature between 1997 and 2024 to identify ethical issues. 33 papers were identified. Several areas of continued ethical debate were delineated: the role of advanced life support techniques; the ethical acceptability of aortic occlusion balloons; the nature and timing of consent to organ preserving techniques; whether best interests can/should extend beyond individual bodily integrity in this context. Further empirical research and ethical analyses are needed in these domains. Broad consensus was identified on several issues including: decisions about termination of resuscitation and entry into a uDCD protocol should be made by different teams; at least 20-30 min of cardio-pulmonary resuscitation is required; a hands-off period of 5-7 min is required alongside continuous monitoring; organ preserving techniques should be as minimally invasive as possible; families should be approached early to discuss organ donation by trained staff; public knowledge and engagement about uDCD is poor and must be improved; transparency and informed consent are essential for potential uDCD organ recipients. To maintain transparency and encourage positive public engagement we propose a name change from uDCD to Organ Donation after Sudden Irreversible Cardiac Arrest (ODASICA).

Indexed as

DeathTissue and Organ ProcurementConsensus Statements as TopicHumansInformed ConsentTissue Donorscardiac arrestethical considerationssystematic literature reviewtransplantuncontrolled donation

Identifiers

PMID39981411
PMCPMC11840875

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.