Evidence map›Paper›PMID 39981401›Full record

ArticleMediators of inflammation2025

Selenium Nanoparticles Decorated With Stevioside Potentially Attenuate Fructose Palmitate Induced Lipid Accumulation in HepG2 Cells.

Shuai Li, Hui Yang, Wenjun Zhou, Ruoting Wang, Likang Li, Changfa Zhang, Jingyi Zhang, Yingxin Liu, Zhi Huang, Guowei Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Mediators of inflammation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Shuai LiMedical Department, Jingchu University of Technology, Jingmen, China.ORCID https://orcid.org/0009-0007-1631-2665
Hui YangDepartment of Health Management of the Guangdong Second Provincial General Hospital and Postdoctoral Research Station of Basic Medicine of the School of Medicine, Jinan University, Guangzhou, China.
Wenjun ZhouMedical Department, Jingchu University of Technology, Jingmen, China.
Ruoting WangCenter for Clinical Epidemiology and Methodology (CCEM), The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, China.
Likang LiCenter for Clinical Epidemiology and Methodology (CCEM), The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, China.
Changfa ZhangCenter for Clinical Epidemiology and Methodology (CCEM), The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, China.
Jingyi ZhangCenter for Clinical Epidemiology and Methodology (CCEM), The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, China.
Yingxin LiuCenter for Clinical Epidemiology and Methodology (CCEM), The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, China.
Zhi HuangDepartment of Health Management of the Guangdong Second Provincial General Hospital and Postdoctoral Research Station of Basic Medicine of the School of Medicine, Jinan University, Guangzhou, China.ORCID https://orcid.org/0000-0002-9698-8652
Guowei LiCenter for Clinical Epidemiology and Methodology (CCEM), The Affiliated Guangdong Second Provincial General Hospital of Jinan University, Guangzhou, China.ORCID https://orcid.org/0000-0002-1184-1791

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The excessive accumulation of lipid droplets within hepatocytes stands as a hallmark characteristic of metabolic-associated fatty liver disease (MAFLD). Selenium (Se) nanoparticles (NPs) have garnered considerable attention for their notable bioavailability, minimal toxicity, and exceptional antioxidant properties. However, a critical limitation lies in the propensity of SeNPs to aggregate into the biologically inactive elemental Se, thereby constraining their utility. Here, we utilized

Indexed as

Diterpenes, KauraneFructoseGlucosidesLipid MetabolismNanoparticlesPalmitatesSeleniumHep G2 CellsHumansOxidative StressDiterpenes, KauraneFructoseGlucosidesPalmitatesSeleniumsteviosideHepG2 cellslipid accumulationMAFLDoxidative stressselenium nanoparticlesstevioside

Identifiers

PMID39981401
PMCPMC11842145

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.