Evidence map›Paper›PMID 39981400›Full record

ArticleMediators of inflammation2025

Herbal Medicine Extracts Improve Motor Function by Anti-Inflammatory Activity in hSOD1

Eun Jin Yang, Sun Hwa Lee

Abstract read
In one paragraph

Article in Mediators of inflammation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Eun Jin YangDepartment of KM Science Research, Korea Institute of Oriental Medicine, Yuseong-gu, Daejeon 34054, Republic of Korea.ORCID https://orcid.org/0000-0002-2963-3923
Sun Hwa LeeDepartment of Clinical Research, Korea Institute of Oriental Medicine, Yuseong-gu, Daejeon 34054, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amyotrophic lateral sclerosis (ALS) is a multicomplex neurodegenerative disorder characterized by motor neuron death, muscle atrophy, and respiratory failure. Owing to its multicomplex mechanisms and multifactorial nature in the skeletal muscle and spinal cord (SC), no effective therapy has been developed. However, herbal medicines, known for their multitarget properties, have demonstrated promising efficacy with limited side effects in treating various diseases. Specifically,

Indexed as

Amyotrophic Lateral SclerosisAnti-Inflammatory AgentsHerbal MedicinePlant ExtractsAnimalsDisease Models, AnimalInflammationMaleMiceMice, TransgenicMotor NeuronsMuscle, SkeletalOxidative StressPaeoniaSpinal CordSuperoxide Dismutase-1Anti-Inflammatory AgentsPlant ExtractsSuperoxide Dismutase-1amyotrophic lateral sclerosisanti-inflammationhSOD1G93A transgenic micemotor functionPaeonia lactiflora Pallas

Identifiers

PMID39981400
PMCPMC11842138

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.