ArticleFrontiers in cellular and infection microbiology2025
Metagenomic next-generation sequencing assists in the diagnosis of visceral leishmaniasis in non-endemic areas of China.
Article in Frontiers in cellular and infection microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- An observational study to test the potency of GLP-grade phenol-free lyophilised leishmanin antigen formulation.EBioMedicine · 2026Article
- Diagnosis of human cutaneous leishmaniasis: comparison between ITS1-PCR and ITS1-219 next generation sequencing.BMC microbiology · 2026Article
- First Imported Case of Cerebral Schistosomiasis Mansoni - China, May 2025.China CDC weekly · 2026Article
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6 authors.
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Abstract
Introduction: Leishmaniasis, a protozoan disease caused by infection by Methods: With the development of metagenomic nextgeneration sequencing (mNGS) technology for pathogen identification, it is possible to detect specific nucleic acid sequences characteristic of Results: Our report demonstrates that the mNGS method is applicable to peripheral blood samples (PB), which are far more readily available in clinical settings, in addition to bone marrow aspirate samples (BM), which are traditionally used for diagnosis of visceral leishmaniasis. Conclusion: Our report validates the efficacy of mNGS technology as a rapid and accurate method of diagnosis for leishmaniasis.
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