ArticleHeliyon2025
Visual detection of cyanide using ninhydrin coated paper.
Article in Heliyon, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Humans are often exposed to cyanide through drinking water or by eating plants that contain cyanogenic glucosides (e.g. cassava - a staple source of carbohydrates). Many methods exist to detect cyanide, but few are safe, cheap and easy to perform for an untrained user. In this work, we demonstrate that Whatman paper can be coated with ninhydrin and that the addition of basic solutions of cyanide gives an immediate pale yellow to red colour change. The ninhydrin paper can be used to visually, semi-quantitatively detect cyanide at concentrations up to ∼5 μg/mL (in 30 μL; 0.15 μg), and can be stored for several months. Most importantly, we show the paper can be used to monitor the release of cyanide from plants such as cassava leaves as they are processed in cooking suggesting the paper could be used in-the-field.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.