Anaphylactic shock induced by intravenous ketorolac: A case report.

Huijuan Lu, Kaili Lai, Shuzhu Lin, Guining Dang

Abstract readCase Reports

In one paragraph

Article in Heliyon, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Huijuan LuDepartment of Orthopedics and Traumatology, Southern Medical University Hospital of Integrated Traditional Chinese and Western Medicine, Guangzhou, China.

Kaili LaiDepartment of Orthopedics and Traumatology, Southern Medical University Hospital of Integrated Traditional Chinese and Western Medicine, Guangzhou, China.

Shuzhu LinDepartment of Orthopedics and Traumatology, Southern Medical University Hospital of Integrated Traditional Chinese and Western Medicine, Guangzhou, China.

Guining DangDepartment of Orthopedics and Traumatology, Southern Medical University Hospital of Integrated Traditional Chinese and Western Medicine, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ketorolac trometamol injection is the first injectable nonsteroidal anti-inflammatory drug (NSAID) approved for the short-term management of moderate to severe pain. As a non-opioid alternative, it represents a critical development for acute pain relief, particularly in postoperative and injury-related scenarios. Like other NSAIDs, ketorolac trometamol is associated with common adverse reactions such as dizziness, headache, drowsiness, nausea, and vomiting, which are generally mild to moderate. However, rare but severe reactions like anaphylactic shock have been reported. This case report highlights a specific instance of anaphylactic shock induced by intravenous ketorolac trometamol, emphasizing the rapid onset of symptoms and the importance of vigilant monitoring during administration to prevent severe outcomes. Additionally, recommendations for post-recovery monitoring and allergological evaluation are provided to enhance clinical management in similar cases.

Indexed as

Adverse drug reactionAnaphylactic shockAnaphylaxisCase reportIntravenous injectionKetorolac trometamol

Identifiers

PMID39981370

DOI10.1016/j.heliyon.2025.e42236

PMCPMC11840493

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LicenceCC BY-NC-ND

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.