ReviewFrontiers in cardiovascular medicine2025
Atrial fibrillation and cognitive impairment: mechanisms, influencing factors, and prospects.
Review in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Neurocardiology: Brain-Heart Interactions in the Heart.MedComm · 2026Review
- Atrial Fibrillation Burden: Assessment, Clinical Significance, and Therapeutic Implications.Life (Basel, Switzerland) · 2026Review
- Oral anticoagulant use and incident dementia in atrial fibrillation by baseline LIBRA score: a population-based cohort study using the 45 and up study.GeroScience · 2026Article
- Ratio of Left Atrial and Ventricular Volume as New Marker of Atrial Cardiopathy and Stroke Risk.Stroke · 2026Article
- Incidence and clinical predictors of cognitive decline in anticoagulated patients with atrial fibrillation: the Strat-AF Study.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2026Article
- Exploring Associations Between Early Cognitive Impairment and Echocardiographic Markers in Middle-Aged Patients with Atrial Fibrillation and Cardiometabolic Comorbidities: A Pilot Study.Clinics and practice · 2026Article
- Association of Permanent Atrial Fibrillation with Cognitive Impairment in Stroke-Censored Patients from Western Romania: A Cross-Sectional Study.Diagnostics (Basel, Switzerland) · 2026Article
- Joint trajectories of sleep quality and cognitive function after acute ischemic stroke: a prospective cohort study using group-based dual trajectory modeling.Frontiers in medicine · 2026Article
- Linking atrial fibrillation to cerebral small vessel disease: a cross-sectional study with predictive analytics.Frontiers in cardiovascular medicine · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Atrial fibrillation (AF) is a prevalent cardiac arrhythmia and a significant contributor to cardioembolic stroke, a condition closely linked to cognitive decline. However, research reveals that AF itself is independently associated with an increased risk of cognitive impairment. This high incidence of cognitive decline in AF patients may result from various mechanisms, including reduced cerebral perfusion, microembolism, decreased cardiac output, and chronic inflammation. Methods: This review synthesizes current evidence on the relationship between AF and cognitive impairment, examines underlying mechanisms of cognitive decline in AF, and explores the roles of AF type, treatment approaches, left atrial characteristics, and associated conditions in cognitive function outcomes. Results: Cognitive outcomes in AF are further influenced by a range of factors, such as left atrial structural parameters, AF type and duration, anticoagulation use, catheter ablation, comorbidities, age, and gender. Discussion: The review highlights the complex interplay between AF and cognitive impairment, emphasizing the importance of understanding the various mechanisms and factors that contribute to cognitive decline in AF patients. By examining the roles of AF type, treatment approaches, left atrial characteristics, and associated conditions, this review provides insights into potential strategies for mitigating cognitive impairment in AF patients.
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