Evidence map›Paper›PMID 39981329›Full record

ArticleEthiopian journal of health sciences2025

Recto Sigmoid Sub-Mucosal Bleeding Due to Warfarin over Anticoagulation Presenting as Intestinal Obstruction.

Fithanegest Teferra Gebretekle, Minyahil Zeleke Tesfaye, Tibebu Tesfaye

Abstract readCase Reports
In one paragraph

Article in Ethiopian journal of health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Fithanegest Teferra GebretekleDepartment of Radiology, St. Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
Minyahil Zeleke TesfayeDepartment of Internal Medicine, Girum General Hospital, Addis Ababa, Ethiopia.
Tibebu TesfayeDepartment of Surgery, Girum General Hospital, Addis Ababa, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients on anticoagulation therapy, particularly those on warfarin, are at risk of gastrointestinal bleeding, gum bleeding, hematuria, and ecchymosis. However, it is rare for such patients to present with intramural or submucosal bleeding leading to intestinal obstructive symptoms. Sub-mucosal intestinal bleeding due to prolonged anticoagulant use is uncommon. Literature suggests that the duodenum and small intestine are common locations for anticoagulant-induced hematomas, occurring in approximately 1 case per 2,500 anticoagulated patients per year. However, intramural colonic hematomas are rarely reported. Spontaneous anticoagulant induced hematomas may develop as early as 10 days after starting therapy. We report the case of a 63-year-old female who presented with recto-sigmoid sub-mucosal bleeding causing obstructive symptoms. The patient was managed surgically with laparotomy, resulting in significant improvement, and was scheduled for follow-up to evaluate the feasibility of reintroducing anticoagulation therapy.

Indexed as

AnticoagulantsGastrointestinal HemorrhageHematomaIntestinal ObstructionWarfarinFemaleHumansMiddle AgedAnticoagulantsWarfarinBleedinghematomaObstructionover anti-coagulation and INRSubmucosalSurgery/LaparotomyWarfarin

Identifiers

PMID39981329
PMCPMC11837791

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.