Rapid onset of myocardial calcification following septic shock due to influenza superinfection: a case report.

Thibaut Gobé, Adrien Werquin, Nicolas Polge, Bernard Cholley

Abstract readCase Reports

In one paragraph

Article in European heart journal. Case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Thibaut GobéDepartment of Anesthesiology and Intensive Care Medicine, Hôpital Européen Georges Pompidou, AP-HP, 20 Rue Leblanc 75015, Paris, France.ORCID https://orcid.org/0000-0002-6077-891X

Adrien WerquinDepartment of Anesthesiology and Intensive Care Medicine, Hôpital Européen Georges Pompidou, AP-HP, 20 Rue Leblanc 75015, Paris, France.ORCID https://orcid.org/0009-0000-1229-207X

Nicolas PolgeDepartment of Anesthesiology and Intensive Care Medicine, Hôpital Européen Georges Pompidou, AP-HP, 20 Rue Leblanc 75015, Paris, France.

Bernard CholleyDepartment of Anesthesiology and Intensive Care Medicine, Hôpital Européen Georges Pompidou, AP-HP, 20 Rue Leblanc 75015, Paris, France.ORCID https://orcid.org/0000-0001-6388-6011

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Myocardial calcification is an unusual complication of septic cardiomyopathy. Dystrophic calcification may occur after damage to myocardial tissue, but its occurrence is rare. Case summary: A 42-year-old pregnant woman with no past medical history was admitted in intensive care for respiratory distress caused by bacterial superinfection of influenza. Subepicardial calcification of the left ventricle appeared on a computed tomography at Day 8. Calcification worsened quickly, but we observed a paradoxical improvement in left ventricle function, as assessed by left ventricular ejection fraction and global longitudinal strain using echocardiography with speckle tracking. Discussion: The pathophysiology of myocardial calcification is not fully understood, but prolonged haemodynamic failure, profound acidosis, high vasopressor doses, and acute respiratory distress syndrome were previously associated with septic-related myocardial calcification.

Indexed as

ARDSCase reportGlobal longitudinal strainMyocardial calcificationSeptic shockSubepicardial calcificationVV-ECMO

Identifiers

PMID39981022

DOI10.1093/ehjcr/ytae609

PMCPMC11839270

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