Evidence map›Paper›PMID 39980864›Full record

ReviewStem cells international2025

Impact of Different Cell Types on the Osteogenic Differentiation Process of Mesenchymal Stem Cells.

Zixin Wang, Lina Ren, Zhengtao Li, Qingyuan Qiu, Haonan Wang, Xin Huang, Dongyang Ma

Abstract readReview
In one paragraph

Review in Stem cells international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Alveolar Bone Regeneration: Smart Biomaterials and Physical Stimulation.Journal of biomedical materials research. Part B, Applied biomaterials · 2026
    Review
  5. Review
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zixin WangSchool of Stomatology, Lanzhou University, Lanzhou, China.ORCID https://orcid.org/0009-0000-3217-8629
Lina RenSchool of Stomatology, Lanzhou University, Lanzhou, China.ORCID https://orcid.org/0009-0008-2188-5289
Zhengtao LiSchool of Stomatology, Lanzhou University, Lanzhou, China.ORCID https://orcid.org/0009-0006-7549-8810
Qingyuan QiuSchool of Stomatology, Lanzhou University, Lanzhou, China.ORCID https://orcid.org/0009-0000-7945-3691
Haonan WangSchool of Stomatology, Lanzhou University, Lanzhou, China.ORCID https://orcid.org/0009-0007-0217-4767
Xin HuangSchool of Stomatology, Lanzhou University, Lanzhou, China.ORCID https://orcid.org/0009-0009-2559-1875
Dongyang MaSchool of Stomatology, Lanzhou University, Lanzhou, China.ORCID https://orcid.org/0009-0003-8863-2669

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The skeleton is an important organ in the human body. Bone defects caused by trauma, inflammation, tumors, and other reasons can impact the quality of life of patients. Although the skeleton has a certain ability to repair itself, the current most effective method is still autologous bone transplantation due to factors such as blood supply and defect size. Modern medicine is attempting to overcome these limitations through cell therapy, with mesenchymal stem cells (MSCs) playing a crucial role. MSCs can be extracted from different tissues, and their differentiation potential varies depending on the source. Various cells and cell secretions can influence this process. This article, based on previous research, reviews the effects of macrophages, endothelial cells (ECs), nerve cells, periodontal cells, and even some bacteria on MSC osteogenic differentiation, aiming to provide a reference for multicell coculture strategies related to osteogenesis.

Indexed as

bone healingmesenchymal stem cellosteogenic differentiationtissue engineering

Identifiers

PMID39980864
PMCPMC11842143

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.