Evidence map›Paper›PMID 39980431›Full record

ReviewPest management science2025

RNAi technology development for weed control: all smoke and no fire?

Silvia Panozzo, Andrea Milani, Serena Bordignon, Laura Scarabel, Serena Varotto

Abstract readReview
In one paragraph

Review in Pest management science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Designer circRNAPlant cell reports · 2025
    Article
  5. RNAi spray-induced gene silencing ofFrontiers in plant science · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Silvia PanozzoInstitute for Sustainable Plant Protection (IPSP), National Research Council of Italy (CNR), Legnaro, Italy.
Andrea MilaniInstitute for Sustainable Plant Protection (IPSP), National Research Council of Italy (CNR), Legnaro, Italy.ORCID https://orcid.org/0000-0002-6379-7737
Serena BordignonDepartment of Agronomy Food Natural Resources, Animals and Environment (DAFNAE), University of Padova, Legnaro, Italy.
Laura ScarabelInstitute for Sustainable Plant Protection (IPSP), National Research Council of Italy (CNR), Legnaro, Italy.ORCID https://orcid.org/0000-0002-2584-3069
Serena VarottoDepartment of Agronomy Food Natural Resources, Animals and Environment (DAFNAE), University of Padova, Legnaro, Italy.

Funding

Next Generation EU
6 · The paper itself

Abstract

RNA interference (RNAi) technology, specifically Spray-Induced Gene Silencing (SIGS), holds potential as an innovative approach for selective weed control, promising environmentally friendly alternatives to traditional herbicides. Although the development of RNAi-based crop protection agents against pathogens, insects and viruses is advancing rapidly, RNAi-based weed control remains in the nascent stages, with challenges in gene target specificity and effective delivery mechanisms. It is potentially a game-changer in agriculture, yet SIGS's applicability is limited by the lack of scientific evidence. The overall aim of this review is to focus attention on critical points that need to be addressed to advance the knowledge about and development of RNAi herbicides, and overcome the poor progress achieved so far. Enhancing RNAi delivery methods and focusing on high impact weed species could transform SIGS into a viable tool for sustainable agriculture. © 2025 The Author(s). Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

Indexed as

Plant WeedsRNA InterferenceWeed ControlHerbicidesHerbicidesdsRNAgene silencing targetmodel weed speciesRNA interferenceweed control

Identifiers

PMID39980431
PMCPMC12159382

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.