Evidence map›Paper›PMID 39980309›Full record

ArticleCancer medicine2025

Comparison of Subjective and Objective Cognitive Function and Emotional State in Supratentorial Brain Tumors Before Surgery-Recognizing the Influence of Laterality.

Lisa Schock, Karsten Wrede, Neriman Oezkan, Philipp Dammann, Marvin Darkwah Oppong, Oliver Gembruch, Ramazan Jabbarli, Ilonka Kreitschmann-Andermahr, Sonja Siegel, Anna Lena Friedel and 5 more

Abstract readComparative Study
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Article in Cancer medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

15 authors.

Lisa SchockDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.ORCID https://orcid.org/0009-0009-0615-5752
Karsten WredeDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Neriman OezkanDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Philipp DammannDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Marvin Darkwah OppongDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Oliver GembruchDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Ramazan JabbarliDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Ilonka Kreitschmann-AndermahrDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Sonja SiegelDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Anna Lena FriedelCenter for Translational Neuro- & Behavioral Sciences (C-TNBS), University of Duisburg-Essen, Essen, Germany.
Adrian EngelDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Hanah Hadice KaradachiDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Lilith Philomena LaflörDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Ulrich SureDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Yahya AhmadipourDepartment of Neurosurgery and Spine Surgery, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

Funding

Foundation University Medicine Essen
6 · The paper itself

Abstract

objectiveBecause of its high prognostic value, neuropsychological assessment plays a crucial role in the neuro-oncology setting. Subjective and objective cognitive performance correlate only to a limited extent, and subjective cognitive performance is strongly dependent on emotional state. We postulate that the relation of subjective and objective cognitive performance depends on tumor laterality.

methodsIn this prospective study, N = 63 patients with brain tumors underwent a neuropsychological test battery, including assessment of subjective cognitive function (attention, memory, executive), and symptoms of depression and anxiety before surgery. Patients with psychiatric comorbidity or severe neurological conditions were excluded.

resultsThere were no significant differences in subjective and objective cognitive function, symptoms of depression and anxiety between left (N = 37) and right (N = 26) hemisphere tumors. All measures of subjective cognitive function correlated highly significantly with symptoms of depression and anxiety in left hemisphere tumor patients (all r ≥ 0.470). In right hemisphere tumor patients, there was no relation between subjective cognitive function and emotional state. Significant laterality differences for correlations of subjective and objective cognitive function were not found and were not significant within the two groups.

conclusionsEven when unbiased by symptoms of anxiety and depression, right hemisphere tumor patients show the same discrepancy in subjective and objective cognitive function as left hemisphere tumor patients. This discrepancy may be based on a different mechanism in right hemisphere tumor patients.

Indexed as

Brain NeoplasmsCognitionEmotionsFunctional LateralitySupratentorial NeoplasmsAdultAgedAnxietyDepressionFemaleHumansMaleMiddle AgedNeuropsychological TestsProspective Studiesanxietybrain tumordepressionlateralitysubjective cognitive function

Identifiers

PMID39980309
PMCPMC11842867

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