Evidence map›Paper›PMID 39980176›Full record

ArticlePhysiological reports2025

A method for MRI-guided bronchoscopy to identify obstructed airway segments.

David G Mummy, Marrissa J McIntosh, Katherine J Carey, Shannon Kehoe, Stephane Esnault, Mats W Johansson, Michael D Evans, Ronald L Sorkness, Mark Schiebler, Nizar N Jarjour and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

David G MummyDepartment of Radiology, Duke University Medical Center, Durham, North Carolina, USA.
Marrissa J McIntoshDepartment of Radiology, University of Iowa, Iowa City, Iowa, USA.
Katherine J CareyDepartment of Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Shannon KehoeDepartment of Medical Physics, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Stephane EsnaultDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Mats W JohanssonDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Michael D EvansClinical and Translational Science Institute, University of Minnesota, Minneapolis, Minnesota, USA.
Ronald L SorknessDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Mark SchieblerDepartment of Radiology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Nizar N JarjourDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Loren C DenlingerDivision of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID https://orcid.org/0009-0008-1299-1186
Sean B FainDepartment of Radiology, University of Iowa, Iowa City, Iowa, USA.ORCID https://orcid.org/0000-0001-5461-0646

Funding

University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Jong Sung Kim · 1990 to 2026
$40.5M
INSTITUTIONAL CTSA (UW-MADISON): CLINICAL TRIALSUL1RR025011 · NCRR · UNIVERSITY OF WISCONSIN-MADISON · PI DREZNER, MARC KENNETH · 2007 to 2011
$29.5M
Using MRI To Visualize Regional Therapy Response In Idiopathic Pulmonary FibrosisR01HL126771 · NHLBI · DUKE UNIVERSITY · PI Bastiaan Driehuys · 2015 to 2026
$6.6M
MRI Phenotyping of Severe BPD and Prediction of OutcomesR01HL146689 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI JASON C WOODS · 2019 to 2026
$4.6M
Dynamic Imaging of Lung Ventilation and Perfusion Using CT and MRIR01HL169765 · NHLBI · UNIVERSITY OF IOWA · PI Sean Bedilion Fain · 2023 to 2026
$2.9M
Nucleotide receptor modulation of airway eicosanoids during asthma exacerbationsR01HL115118 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI DENLINGER, LOREN C · 2013 to 2017
$2.4M
Viral Induced Asthma ExacerbationsR01HL080412 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI JARJOUR, NIZAR N · 2005 to 2009
$2.0M
HHS | National Institutes of Health (NIH) HL080412HHS | National Institutes of Health (NIH) HL115118HHS | National Institutes of Health (NIH) HL126771HHS | National Institutes of Health (NIH) HL146689HHS | National Institutes of Health (NIH) HL169765National Center for Advancing Translational Sciences (NCATS) UL1RR025011NCATS NIH HHS UL1 TR002373NCRR NIH HHS UL1 RR025011NHLBI NIH HHS R01 HL080412NHLBI NIH HHS R01 HL115118NHLBI NIH HHS R01 HL126771NHLBI NIH HHS R01 HL146689NHLBI NIH HHS R01 HL169765NIEHS NIH HHS P30 ES005605William W. and Judith H. Busse Professorship in Allergy and Asthma Research
6 · The paper itself

Abstract

Bronchoscopy is not conventionally guided by prior knowledge of segmental airway obstruction. Hyperpolarized gas magnetic resonance imaging (MRI) ventilation abnormalities and computed tomography (CT) air trapping are related to lung function and asthma severity but have not been used to target segmental inflammation and remodeling. We evaluate the feasibility of using bronchoscopy guided by

Indexed as

Airway ObstructionAsthmaBronchoscopyLungMagnetic Resonance ImagingAdultFemaleHumansMaleTomography, X-Ray ComputedYoung Adultasthmabronchial wall biopsybronchoalveolar lavageCT air trappinghyperpolarized gas MRI

Identifiers

PMID39980176
PMCPMC11842447

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.