Evidence map›Paper›PMID 39980170›Full record

ArticleThe Journal of clinical endocrinology and metabolism2025

Secular Trends in Hip Fracture Mortality and Predictors of Mortality From the NSQIP Database.

Caline Rhayem, Aya Ghosn, Zeinab Ali Issa, Joudie Sahar Alwan, Hani Dimassi, Rachid Haidar, Ghada El-Hajj Fuleihan

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Article in The Journal of clinical endocrinology and metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Caline RhayemDivision of Endocrinology, American University of Beirut Medical Center, 1107 2020 Beirut, Lebanon.ORCID 0009-0004-1411-5121
Aya GhosnDivision of Endocrinology, Memorial Sloan Kettering, New York, NY 10065, USA.ORCID 0009-0003-5727-2613
Zeinab Ali IssaDivision of Endocrinology, American University of Beirut Medical Center, 1107 2020 Beirut, Lebanon.ORCID 0009-0000-0174-7454
Joudie Sahar AlwanDepartment of Pediatric Emergency Medicine, Children's Hospital of Michigan, Detroit, MI 48201, USA.
Hani DimassiDepartment of Pharmaceutical Sciences, School of Pharmacy, Lebanese American University, P.O. Box 36, Byblos, Lebanon.
Rachid HaidarDivision of Orthopedic Surgery, American University of Beirut Medical Center, 1107 2020 Beirut, Lebanon.
Ghada El-Hajj FuleihanDivision of Endocrinology, American University of Beirut Medical Center, 1107 2020 Beirut, Lebanon.ORCID 0000-0002-2076-5858

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Genetic and Metabolic Determinants of 25(OH)D levels at Baseline and One Year: Findings from a Dose Ranging Vitamin D trialD43TW009118 · FIC · AMERICAN UNIVERSITY OF BEIRUT · PI FULEIHAN, GHADA ELHAJJ · 2012 to 2024
$2.5M
FIC NIH HHS D43 TW009118NCI NIH HHS P30 CA008748Scholars in HeAlth Research Program
6 · The paper itself

Abstract

contextHip fractures incur high morbidity and mortality. Data on secular trends in mortality from hip fractures and risk predictive models are scarce.

objectiveWe aim to describe secular trends in 30-day mortality after hip fracture surgery from the 2011-2017 National Surgical Quality Improvement Program database, identify preoperative and on-discharge predictors of 30-day mortality, and develop risk calculators.

methodsWe calculated yearly proportions of deaths and examined survival using Kaplan-Meier curves. We implemented logistic regressions models, using SPSS and created calculators using Excel.

resultsIn 84 824 cases of hip fracture surgery, the overall 30-day mortality was 6.8%. It decreased from 8.1% to 6.5% between 2011 and 2017 (P < .001). Significant preoperative predictors of 30-day mortality on admission were male gender, age, lower body mass index, White race, poorer functional health status, higher creatinine, lower hematocrit, >10% weight loss in the past 6 months, congestive heart failure within 30 days before surgery, and chronic obstructive pulmonary disease. Predictors on discharge included preoperative predictors with the exception of White race, hematocrit, and >10% weight loss in the past 6 months, and the addition of unplanned intubation, cerebrovascular accident, myocardial infarction, and pneumonia. The parsimonious preoperative risk calculator for mortality had 10 variables, an area under the curve (AUC) of 0.739, and a model fit R2 of 0.9716. The on-discharge calculator had 11 variables, an AUC of 0.800, and an R2 of 0.9924.

conclusionThirty-day mortality after hip fracture surgery decreased significantly from 2011 to 2017. Readily available clinical risk factors predict mortality preoperatively and on discharge. While most predictors are nonmodifiable, the calculators may better inform clinical decision-making.

Indexed as

Hip FracturesAgedAged, 80 and overDatabases, FactualFemaleHumansKaplan-Meier EstimateMaleMiddle AgedMortalityPrognosisQuality ImprovementRisk AssessmentRisk FactorsUnited Stateship fracturemortality predictorsmortality risksecular trends

Identifiers

PMID39980170
PMCPMC12527425

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.