Evidence map›Paper›PMID 39980078›Full record

ArticlePersonality and mental health2025

Mental Health and Personality Functioning of People With Probable Personality Disorder Who Have Coexisting Complex Post Traumatic Stress Disorder.

Sapphira McBride, Nia Goulden, Kirsten Barnicot, Kieron Corrigan, Sophie Shen, Serena Guillemard, Violet Effiom, Gemma Harrison, Lizwi Nyathi, Lyn Charles and 4 more

Abstract read
In one paragraph

Article in Personality and mental health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Sapphira McBrideDivision of Psychiatry, Imperial College London, London, UK.
Nia GouldenNorth Wales Organisation for Randomised Trials in Health, Bangor University, Bangor, Gwynedd, UK.ORCID 0000-0001-6511-3987
Kirsten BarnicotSchool of Health & Medical Sciences, St George's, University of London, London, UK.
Kieron CorriganAvon and Wiltshire Mental Health Partnership NHS Trust, Research and Development, Blackberry Hill Hospital, Bristol, UK.
Sophie ShenResearch and Development, Mersey Care NHS Foundation Trust, Hollins Park, Warrington, UK.
Serena GuillemardDepartment of Psychiatry, University of Oxford, Headington, UK.
Violet EffiomResearch Department, Coventry and Warwickshire Partnership Trust (CWPT), Coventry, UK.
Gemma HarrisonCentre for Research and Development, Derbyshire Healthcare NHS Foundation Trust, Kingsway Hospital, Derbyshire, UK.
Lizwi NyathiClinical Research Office, Lincolnshire Partnership NHS Foundation Trust, Lincoln, UK.
Lyn CharlesClinical Research Office, Lincolnshire Partnership NHS Foundation Trust, Lincoln, UK.
Snehal P PandyaDivision of Psychiatry, Imperial College London, London, UK.ORCID 0009-0000-8173-1486
Verity LeesonDivision of Psychiatry, Imperial College London, London, UK.
Rachel EvansNorth Wales Organisation for Randomised Trials in Health, Bangor University, Bangor, Gwynedd, UK.
Mike J CrawfordDivision of Psychiatry, Imperial College London, London, UK.

Funding

National Institute for Health: Health Technology Assessment NIHR133027NIHR Imperial Biomedical Research Centre
6 · The paper itself

Abstract

This paper examines the prevalence and comorbidity of complex post-traumatic stress disorder (CPTSD) and borderline personality disorder (BPD) among individuals with probable personality disorder, using baseline data from the Structured Psychological Support clinical trial. The clinical characteristics and personality functioning of participants are summarised and compared between those meeting criteria for BPD, CPTSD, both or neither condition. Among 292 participants, 97% reported significant trauma exposure, and over half met the criteria for CPTSD. Those with CPTSD exhibited higher levels of social dysfunction and depression compared with those with BPD, despite both groups showing elevated emotion dysregulation and anxiety. Comorbidity of CPTSD and BPD was high, with 50% of the sample meeting criteria for both conditions. Participants with comorbid CPTSD and BPD displayed poorer baseline scores across all measures of mental health and functioning than those who met criteria for BPD alone. No statistically significant differences were found in suicidal behaviour or treatment-seeking between groups. There were no significant differences in International Classification of Diseases-11 personality trait domains between participants with CPTSD and BPD, but people with comorbid CPTSD and BPD displayed higher levels of trait negative affectivity than those with BPD alone. The findings highlight the need for trauma-informed assessments in clinical settings and a better understanding of the impact of CPTSD on treatment outcomes for people with personality disorder, including how existing treatments may need to be modified to better meet the needs of people with these highly comorbid conditions.

trial registrationCurrent controlled trials ISRCTN13918289 (registered 11/11/2022).

Indexed as

Borderline Personality DisorderPersonality DisordersStress Disorders, Post-TraumaticAdultComorbidityFemaleHumansMaleMiddle AgedYoung Adultborderline personality disordercomorbiditycomplex post‐traumatic stress disorderpersonality disordertrauma

Identifiers

PMID39980078
PMCPMC11842586

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.