Evidence map›Paper›PMID 39979896›Full record

Trial reportBMC complementary medicine and therapies2025

Effects of Liuzijue Qigong on respiratory function among patients with Parkinson's disease: a randomized clinical trial.

Huimei Yin, Oumei Cheng, Xu Zhang, Fengying Quan, Yujiao Zhang, Hongzhou Zuo, Jianrong Zhou, Shi-Qi Xie

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC complementary medicine and therapies, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Huimei YinDepartment of nursing, the first Affiliated Hospital of Chongqing medical University, Chongqing, 400016, China.ORCID http://orcid.org/0000-0003-3624-7016
Oumei ChengDepartment of Neurology, the first Affiliated Hospital of Chongqing medical University, Chongqing, 400016, China.
Xu ZhangDepartment of nursing, the first Affiliated Hospital of Chongqing medical University, Chongqing, 400016, China.
Fengying QuanDepartment of nursing, the first Affiliated Hospital of Chongqing medical University, Chongqing, 400016, China.
Yujiao ZhangDepartment of Neurology, the first Affiliated Hospital of Chongqing medical University, Chongqing, 400016, China.
Hongzhou ZuoDepartment of Neurology, the first Affiliated Hospital of Chongqing medical University, Chongqing, 400016, China.
Jianrong ZhouCollege of Nursing, Chongqing medical University, No.1, Yixueyuan Road, Yuzhong District, Chongqing city, 400016, China. 202028@cqmu.edu.cn.ORCID http://orcid.org/0000-0002-3612-1264
Shi-Qi XieCollege of Nursing, Chongqing medical University, No.1, Yixueyuan Road, Yuzhong District, Chongqing city, 400016, China. 102835@cqmu.edu.cn.ORCID http://orcid.org/0000-0002-4100-1267

Funding

Chongqing medical scientific research project (Joint project of Chongqing Health Commission and Science and Technology Bureau) 2022MSXM182Chongqing Medical University Nursing School 2023 Scientific Research Project 20230303
6 · The paper itself

Abstract

backgroundRespiratory dysfunction is a common nonmotor symptom in patients with Parkinson's disease that may be easily overlooked. Incorporating respiratory function rehabilitation into routine rehabilitation programs for these patients is important. However, previous studies have focused primarily on professional devices and training processes that require additional professional guidance, making wide implementation challenging.

methodsIn this assessor-masked, randomized clinical trial, eligible participants were randomized into an experimental group and a control group. The experimental group received Liu Zi Jue Qigong exercise for 12 weeks, while the control group underwent conventional rehabilitation exercises. Primary outcomes included measures of respiratory function, such as forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1), the ratio of forced expiratory volume in 1 s to forced vital capacity(FEV1/FVC), peak expiratory flow (PEF), maximal inspiratory pressure (MIP), and maximal expiratory pressure (MEP). Secondary outcomes included motor symptoms, quality of life, depression, and anxiety.

resultsThe results from a study involving 51 Parkinson's disease patients showed significant improvements in the FVC, FEV1, PEF, and MEP in the experimental group compared to those in the control group after the 12-week intervention. Additionally, there was a noticeable decrease in depression and anxiety scores in the experimental group, with statistically significant reductions compared to those in the control group.

conclusionsLiuzijue Qigong exercise has the potential to enhance respiratory function and mental health in patients with Parkinson's disease in the early and middle stages. These findings could serve as a valuable reference for implementing home-based rehabilitation techniques for individuals with Parkinson's disease.

trial registrationChinese Clinical Trial Registry: ChiCTR2200056762(Retrospectively registered, Registration Date: February 15, 2022).

Indexed as

Parkinson DiseaseQigongAgedFemaleHumansMaleMiddle AgedQuality of LifeRespiratory Function TestsLiuZijueParkinson’s diseaseQigongQuality of lifeRespiratory function

Identifiers

PMID39979896
PMCPMC11843974

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.