Evidence map›Paper›PMID 39979770›Full record

ArticleCancer causes & control : CCC2025

Integrating healthcare utilization databases for cancer ascertainment in a prospective cohort in a limited resource setting: the Mexican Teachers' Cohort.

Liliana Gómez-Flores-Ramos, Marion Brochier, Dalia Stern, Antonio García-Anaya, Adrian Cortés-Valencia, Jocelyn Jaen, Hugo R Sánchez-Blas, Susana Lozano-Esparza, Andrés Catzin-Kuhlmann, Juan Eugenio Hernández-Ávila and 12 more

Abstract read
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In one paragraph

Article in Cancer causes & control : CCC, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Mexican Teachers' Cohort Cognitive Study: A pilot of home-based assessments.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Liliana Gómez-Flores-RamosCONAHCYT, Centro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública, Cuernavaca, Morelos, Mexico.
Marion BrochierFaculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Québec, Canada.
Dalia SternCONAHCYT, Centro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública, Cuernavaca, Morelos, Mexico.
Antonio García-AnayaCentro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública, Fray Pedro de Gante 12, Belisario Domínguez Secc 16, Tlalpan, 14080, Mexico City, Mexico.
Adrian Cortés-ValenciaCentro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública, Fray Pedro de Gante 12, Belisario Domínguez Secc 16, Tlalpan, 14080, Mexico City, Mexico.
Jocelyn JaenCentro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública, Fray Pedro de Gante 12, Belisario Domínguez Secc 16, Tlalpan, 14080, Mexico City, Mexico.
Hugo R Sánchez-BlasCentro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública, Fray Pedro de Gante 12, Belisario Domínguez Secc 16, Tlalpan, 14080, Mexico City, Mexico.
Susana Lozano-EsparzaDepartment of Epidemiology, University of Washington, Seattle, WA, USA.
Andrés Catzin-KuhlmannDepartment of Medicine, National Institute of Medical Sciences and Nutrition, Mexico City, Mexico.
Juan Eugenio Hernández-ÁvilaCentro de Investigación en Evaluación y Encuestas, Instituto Nacional de Salud Pública, Cuernavaca, Morelos, Mexico.
Angélica PonDirección Médica, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Gobierno y Municipios del Estado de Baja California (ISSSTECali), Mexicali, Baja California, Mexico.
Olga Rivera-OntiverosDirección Médica, Instituto de Seguridad Social de los Trabajadores del Estado de Chiapas (ISSTECh), Tuxtla Gutiérrez, Chiapas, Mexico.
Pabel Miranda-AguirreCentro Médico Nacional 20 de Noviembre, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE), Mexico City, Mexico.
Patricia Pérez-EscobedoDirección Médica, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE), Mexico City, Mexico.
Alberto CastellanosDirección de Administración y Finanzas, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE), Mexico City, Mexico.
Mildred Chávez-CárdenasDirección Médica, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (ISSSTE), Mexico City, Mexico.
Oscar ArrietaUnidad Funcional de Oncología Torácica, Instituto Nacional de Cancerología (INCan), Mexico City, Mexico.
Alejandro MoharInstituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México (UNAM), Mexico City, Mexico.
Ruy López-RidauraSubsecretaría de Prevención y Promoción de la Salud, Secretaría de Salud, Mexico City, Mexico.
Isabelle RomieuCentro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública, Fray Pedro de Gante 12, Belisario Domínguez Secc 16, Tlalpan, 14080, Mexico City, Mexico.
Mauricio Hernández-AvilaDirección de Prestaciones Económicas y Sociales, Instituto Mexicano del Seguro Social (IMSS), Mexico City, Mexico.
Martín LajousCentro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública, Fray Pedro de Gante 12, Belisario Domínguez Secc 16, Tlalpan, 14080, Mexico City, Mexico. mlajous@insp.mx.

Funding

American Institute for Cancer Research 635420
6 · The paper itself

Abstract

purposeProspective cohort development in low-resource settings may be limited by cancer registry population coverage; however, information routinely collected in health systems may offer opportunities to advance cancer research. We aim to illustrate in a cohort study in Mexico, a cancer ascertainment strategy that integrates multiple sources of information including healthcare utilization databases.

methodsThe Mexican Teachers' Cohort (MTC) includes 114,545 female teachers aged 25 years and older who completed a baseline questionnaire between 2006 and 2010 and were breast cancer free. We used healthcare utilization databases (including electronic health records), self-reported breast cancer, mortality, and cancer registries to identify women with incident breast cancer. We estimated the positive predictive value for self-reported breast cancer and age-specific and age-standardized incidence rates for breast cancer and corresponding 95% confidence intervals (95%CI) calculating person-time from the date of baseline questionnaire response to diagnosis, death, or December 31, 2019.

resultsBetween baseline and 2019, we identified 1,313 women with incident breast cancer. We established the diagnosis in 88% using healthcare utilization databases, 6% using cancer and mortality registries, and 6% directly by contacting participants. The positive predictive value of self-reported diagnosed and treated breast cancer was 94% (95%CI 91, 97). The age-standardized incidence was 77.0 per 100,000 person-years (95%CI 75.9, 84.3). The highest incidence was observed in women aged 65-69 years (185.3 per 100,000 person-years).

conclusionLeveraging healthcare utilization databases to establish cancer diagnoses within prospective cohorts may offer an opportunity to advance global cancer research.

Indexed as

Breast NeoplasmsDatabases, FactualPatient Acceptance of Health CareSchool TeachersAdultAgedFemaleHumansIncidenceMexicoMiddle AgedProspective StudiesRegistriesSurveys and QuestionnairesBreast cancerCohortHealthcare utilization databasesLMICProspective

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.