ArticleEuropean journal of clinical nutrition2025
Association of GLIM-defined malnutrition with depressive mood in older adults undergoing rehabilitation.
Article in European journal of clinical nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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Who cites it
1 citing paper in PubMed.
- Mental Health and Kidneys: The Interplay Between Cognitive Decline, Depression, and Kidney Dysfunction in Hospitalized Older Adults.Journal of clinical medicine · 2025Article
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Authors and funding
10 authors.
Funding
Abstract
BACKGROUND/
objectivesDepressive mood is prevalent in geriatric patients who undergo rehabilitation. Malnutrition, which frequently coexists in this demographic group, likely affects mental health status significantly. This study examined the association between malnutrition and depressive mood at discharge in geriatric patients who were undergoing rehabilitation and identified the mediating roles of specific malnutrition components in this association. SUBJECTS/
methodsThis prospective cohort study comprised 189 geriatric rehabilitation patients. Malnutrition was determined using the Global Leadership Initiative on Malnutrition (GLIM) criteria, and depressive mood was assessed using the Geriatric Depression Scale-15 (GDS-15). The potential mediation of the GLIM components in the relationship between malnutrition and depressive mood was evaluated using causal mediation analysis.
resultsMalnutrition was positively associated with increased GDS-15 scores at both admission (p = 0.007) and discharge (p < 0.001). The severity of malnutrition corresponded with increased odds of depressive mood at discharge (moderate malnutrition: odds ratio [OR] 3.84, 95% confidence interval [CI] 1.48-9.94, p = 0.005; severe malnutrition: OR 5.11, 95% CI 1.52-15.17, p = 0.003). Notably, both muscle mass reduction (OR 1.51, 95% CI 1.01-2.27, p = 0.042) and disease burden (OR 1.37, 95% CI 1.00-1.89, p = 0.047) were identified as mediators in the association between malnutrition and depressive mood at discharge.
conclusionsNutritional status significantly influenced the mental health of geriatric rehabilitation patients, with muscle mass reduction and disease burden mediating this relationship. These findings emphasize the importance of a multidimensional geriatric rehabilitation approach that includes nutritional interventions.
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