Evidence map›Paper›PMID 39979620›Full record

ArticleSurgical endoscopy2025

Pouch outcomes after minimally invasive vs. open proctectomy during IPAA reconstruction.

Daniel Aryeh Metzger, Andrea Mesiti, Josh Johnson, Ying Li, Julianna Brouwer, Morgan Manasa, Sarah Lee, Angela Hsu, Mehraneh D Jafari, Alessio Pigazzi

Abstract readComparative StudyMulticenter Study
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daniel Aryeh MetzgerDepartment of Surgery, New York-Presbyterian/Weill Cornell Medicine, 1300 York Ave, New York, NY, 10065, USA. dnm9112@med.cornell.edu.ORCID 0000-0002-4812-8332
Andrea MesitiDepartment of Surgery, New York-Presbyterian/Weill Cornell Medicine, 1300 York Ave, New York, NY, 10065, USA.
Josh JohnsonDepartment of Surgery, New York-Presbyterian/Weill Cornell Medicine, 1300 York Ave, New York, NY, 10065, USA.
Ying LiDepartment of Public Health, NY-Presbyterian/Weill Cornell Medicine, New York, NY, USA.
Julianna BrouwerDepartment of Surgery, New York-Presbyterian/Weill Cornell Medicine, 1300 York Ave, New York, NY, 10065, USA.
Morgan ManasaDepartment of Surgery, University of California San Francisco, San Francisco, USA.
Sarah LeeDepartment of Surgery, Sutter Roseville Medical Center, Roseville, USA.
Angela HsuSan Jose Gastroenterology, San Jose, USA.
Mehraneh D JafariDepartment of Surgery, New York-Presbyterian/Weill Cornell Medicine, 1300 York Ave, New York, NY, 10065, USA.
Alessio PigazziDepartment of Surgery, City of Hope Orange County Lennar Foundation Cancer Center, Irvine, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere is limited data on pouch outcomes after minimally invasive (MIS) proctectomy during ileal pouch-anal anastomosis (IPAA). This study aimed to determine if MIS proctectomy is associated with differences in pouch complications compared to open.

methodsWe performed a retrospective cohort study of patients from two academic institutions (2010-2022) who underwent restorative proctectomy with IPAA for inflammatory bowel disease, excluding those with Crohn's disease or Crohn's-like disease of the pouch. Patients were categorized into Open and MIS groups based on surgical approach. Perioperative outcomes and rates of pouchitis, cuffitis, and pouch failure were compared. Patient, disease, and operative factors associated with risk of pouch complications were identified using multivariable regression.

results117 patients were included: 36 MIS and 81 Open. Median age at colectomy was 35 years, and 60% were male. Demographics, preoperative symptoms, medications, and surgical indications were comparable between groups. Rates of pouchitis (MIS 37% vs. Open 45%; p = 0.4), cuffitis (32% vs. 27%; p = 0.5), and pouch failure (5.6% vs. 6.2%; p > 0.9) were similar. MIS was associated with lower estimated blood loss (median 75 cc vs. 150 cc; p < 0.001). There were no differences in length of stay (MIS: 5 days vs. Open: 6 days; p = 0.2), operative time, or 30-day postoperative complications (HR 1.41; p = 0.5). There was a trend toward fewer anastomotic leaks in the MIS group (2.1% vs. 9.7%; p-0.2). On multivariable analysis, only initial colectomy for an indication of acute severe ulcerative colitis (HR 6.21; p = 0.044) and

conclusionsMIS proctectomy is associated with equivalent long-term pouch outcomes compared to open proctectomy. There may be a reduced risk of anastomotic leak with MIS and other perioperative outcomes were similar between groups. Patient and disease factors, but not operative factors, were associated with risk of pouch complications.

Indexed as

Colonic PouchesInflammatory Bowel DiseasesPostoperative ComplicationsPouchitisProctocolectomy, RestorativeAdultFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment OutcomeIleal pouch-anal anastomosisMinimally invasivePouchitis

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.