Evidence map›Paper›PMID 39979606›Full record

ArticleArchives of microbiology2025

Saccharomyces cerevisiae fermentation of high molecular weight hyaluronic acid enhanced the antioxidant capacity in skin fibroblasts.

Meng Zhang, Doudou Shi, Mimi Cui, Jinyong Li, Wenjing Cheng, Chunhong Pu, Jiachan Zhang, Changtao Wang

Abstract read
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In one paragraph

Article in Archives of microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Hyaluronidases improve the hyaluronic acid yield during the fermentation ofFrontiers in bioengineering and biotechnology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Meng ZhangSchool of Light Industry Science and Engineering, Beijing Technology and Business University, 11 Fucheng Road, Haidian District, Beijing, 100048, China.
Doudou ShiBeishang Jiamei (Beijing) Technology Co. Ltd, Beijing, 100037, China.
Mimi CuiBeishang Jiamei (Beijing) Technology Co. Ltd, Beijing, 100037, China.
Jinyong LiSchool of Light Industry Science and Engineering, Beijing Technology and Business University, 11 Fucheng Road, Haidian District, Beijing, 100048, China.
Wenjing ChengSchool of Light Industry Science and Engineering, Beijing Technology and Business University, 11 Fucheng Road, Haidian District, Beijing, 100048, China.
Chunhong PuSchool of Light Industry Science and Engineering, Beijing Technology and Business University, 11 Fucheng Road, Haidian District, Beijing, 100048, China.
Jiachan ZhangSchool of Light Industry Science and Engineering, Beijing Technology and Business University, 11 Fucheng Road, Haidian District, Beijing, 100048, China. xiaochan8787@163.com.
Changtao WangSchool of Light Industry Science and Engineering, Beijing Technology and Business University, 11 Fucheng Road, Haidian District, Beijing, 100048, China. wangct@btbu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, fermented hyaluronic acid (FHA) was obtained by fermentation of hyaluronic acid (HA) with molecular weight ranging from 1200 to 1300 kDa with two strains of Saccharomyces cerevicae (CICC 1308 and CICC 1747). Active substance content and spectral analysis revealed a substantial decrease in FHA molecular weight, accompanied by changes in monosaccharide composition, yet the chemical structure of FHA remained unchanged. Secondly, FHA exhibited a strong ability to scavenge 1,1-diphenyl-2-picrylhydrazyl (DPPH) and hydroxyl radicals. In hydrogen peroxide (H

Indexed as

AntioxidantsFibroblastsHyaluronic AcidSaccharomyces cerevisiaeSkinCatalaseFermentationHumansHydrogen PeroxideMolecular WeightNF-E2-Related Factor 2Oxidative StressSignal TransductionSuperoxide DismutaseAntioxidantsCatalaseHyaluronic AcidHydrogen PeroxideNF-E2-Related Factor 2Superoxide DismutaseAntioxidant activityFermentationLow molecular weight of Hyaluronic acidSaccharomyces cerevisiae

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.