Evidence map›Paper›PMID 39979604›Full record

ArticleLeukemia2025

Distinct leukemogenic mechanism of acute promyelocytic leukemia based on genomic structure of PML::RARα.

Mariko Minami, Teppei Sakoda, Gentaro Kawano, Yu Kochi, Kensuke Sasaki, Takeshi Sugio, Fumiaki Jinnouchi, Kohta Miyawaki, Yuya Kunisaki, Koji Kato and 3 more

Abstract read
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In one paragraph

Article in Leukemia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mariko MinamiDepartment of Medicine and Biosystemic Sciences, Kyushu University Graduate School of Medicine, Fukuoka, 812-8582, Japan.
Teppei SakodaDepartment of Medicine and Biosystemic Sciences, Kyushu University Graduate School of Medicine, Fukuoka, 812-8582, Japan.
Gentaro KawanoDepartment of Medicine and Biosystemic Sciences, Kyushu University Graduate School of Medicine, Fukuoka, 812-8582, Japan.
Yu KochiDepartment of Medicine and Biosystemic Sciences, Kyushu University Graduate School of Medicine, Fukuoka, 812-8582, Japan.
Kensuke SasakiDepartment of Medicine and Biosystemic Sciences, Kyushu University Graduate School of Medicine, Fukuoka, 812-8582, Japan.ORCID http://orcid.org/0000-0003-1302-3511
Takeshi SugioDepartment of Medicine and Biosystemic Sciences, Kyushu University Graduate School of Medicine, Fukuoka, 812-8582, Japan.
Fumiaki JinnouchiDepartment of Medicine and Biosystemic Sciences, Kyushu University Graduate School of Medicine, Fukuoka, 812-8582, Japan.
Kohta MiyawakiDepartment of Medicine and Biosystemic Sciences, Kyushu University Graduate School of Medicine, Fukuoka, 812-8582, Japan.
Yuya KunisakiDepartment of Medicine and Biosystemic Sciences, Kyushu University Graduate School of Medicine, Fukuoka, 812-8582, Japan.
Koji KatoDepartment of Medicine and Biosystemic Sciences, Kyushu University Graduate School of Medicine, Fukuoka, 812-8582, Japan.
Toshihiro MiyamotoDepartment of Hematology, Faculty of Medicine, Institute of Medical Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, 920-8641, Japan.
Koichi AkashiDepartment of Medicine and Biosystemic Sciences, Kyushu University Graduate School of Medicine, Fukuoka, 812-8582, Japan. akashi.koichi.357@m.kyushu-u.ac.jp.ORCID http://orcid.org/0000-0001-7763-5723
Yoshikane KikushigeDepartment of Medicine and Biosystemic Sciences, Kyushu University Graduate School of Medicine, Fukuoka, 812-8582, Japan.ORCID http://orcid.org/0000-0002-7721-1696

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Leukemic stem cells (LSCs) of acute myeloid leukemia (AML) can be enriched in the CD34

Indexed as

Leukemia, Promyelocytic, AcuteOncogene Proteins, FusionRetinoic Acid Receptor alphaADP-ribosyl Cyclase 1AnimalsAntigens, CD34Hepatitis A Virus Cellular Receptor 2HumansMiceNeoplastic Stem CellsPromyelocytic Leukemia ProteinADP-ribosyl Cyclase 1Antigens, CD34HAVCR2 protein, humanHepatitis A Virus Cellular Receptor 2Oncogene Proteins, FusionPML protein, humanPromyelocytic Leukemia Proteinpromyelocytic leukemia-retinoic acid receptor alpha fusion oncoproteinRetinoic Acid Receptor alpha

Identifiers

PMID39979604

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.