ArticleScientific reports2025
Relationship between vascular aging and left ventricular geometry in patients with obstructive sleep apnea hypopnea syndrome-related hypertension.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.
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Who cites it
6 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Association of electronic cigarette use and risk of COPD: a systematic review and meta-analysis.NPJ primary care respiratory medicine · 2025Pooled it
- Impact of electronic cigarette use and sleep duration, sleep issues and insomnia: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Machine Learning-Derived Cardiovascular Aging Phenotypes From Cardiac Function and Stroke Risk in the UK Biobank: Cohort Study.JMIR aging · 2026Article
- Impact of kimura-takemoto atrophy classification on first-lineFrontiers in medicine · 2026Article
- Prolonged intermittent hypoxia accelerates cardiovascular aging and mortality: insights from a murine model of OSA.npj aging · 2025Article
- Weighted gene co-expression network analysis identifies functional modules related to bovine respiratory disease.PloS one · 2025Article
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7 authors.
Funding
Abstract
This study aimed to investigate the association of the vascular aging and left ventricular geometry in OSAHS-related hypertension population with good blood pressure control. A retrospective study was conducted at the Third Xiangya Hospital, collecting data from patients admitted between August 1, 2022, and January 1, 2024. Vascular aging parameters were collected, including ankle-brachial index (ABI), brachial-ankle pulse wave velocity (baPWV), and carotid intima-media thickness (cIMT). Left ventricular mass index (LVMI), relative wall thickness (RWT), left ventricular hypertrophy (LVH), and left ventricular concentric geometry (LVCG) were collected to assess left ventricular geometry patterns. Spearman correlation analysis, generalized linear regression, and logistic regression were used to assess the associations of the vascular aging and left ventricular geometry. A total of 238 patients were included. Significant positive correlations were found between baPWV and LVMI (Rs = 0.26, P < 0.001), baPWV and RWT (Rs = 0.37, P < 0.001), cIMT and LVMI (Rs = 0.24, P < 0.001), and cIMT and RWT (Rs = 0.34, P < 0.001). Generalized linear regression model indicated that both baPWV (β = 0.84, P = 0.01 for LVMI; β = 0.005, P < 0.001 for RWT) and cIMT (β = 27.54, P = 0.01 for LVMI; β = 0.13, P < 0.001 for RWT) were associated with LVMI and RWT, respectively. Logistic regression revealed that baPWV (OR = 1.08, 95%CI 1.02-1.15) and cIMT (OR = 1.30, 95%CI 1.06-1.60) were associated with LVH. baPWV (OR = 1.44, 95%CI 1.28-1.65) and cIMT (OR = 1.54, 95%CI 1.21-1.96) also showed associations with LVCG. Subgroup analyses based on gender and BMI suggested that the results were robust. This study showed that vascular aging parameters may be used to assess changes in left ventricular geometry of patients with OSAHS-related hypertension.
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