Evidence map›Paper›PMID 39979349›Full record

ArticleScientific reports2025

Prevalence of erectile dysfunction as long-COVID symptom in hospitalized Japanese patients.

Hideaki Kato, Nao Ichihara, Hiroki Saito, Shigeki Fujitani, Kohei Ota, Yuji Takahashi, Toshiyuki Harada, Takeshi Hattori, Mitsuru Komeya, Mariko Hosozawa and 6 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Hideaki KatoInfection Prevention and Control Department, Yokohama City University Hospital, 3-9 Fukuura, Kanazawa-ku, Yokohama, Kanagawa, 236-0004, Japan. ekato@yokohama-cu.ac.jp.
Nao IchiharaDepartment of Medical Innovation, University of Osaka Graduate School of Medicine, Osaka, Japan.
Hiroki SaitoDepartment of Emergency and Critical Care Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
Shigeki FujitaniDepartment of Emergency and Critical Care Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
Kohei OtaDepartment of Emergency and Critical Care Medicine, Graduate School of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan.
Yuji TakahashiDepartment of Emergency and Critical Care Medicine, Hitachi General Hospital, Hitachi, Japan.
Toshiyuki HaradaCenter for Respiratory Diseases, Japan Community Healthcare Organization, Hokkaido Hospital, Sapporo, Japan.
Takeshi HattoriDepartment of Respiratory Medicine, National Hospital Organization Hokkaido Medical Center, Sapporo, Japan.
Mitsuru KomeyaDepartment of Urology, Yokohama City University Hospital, Yokohama, Japan.
Mariko HosozawaInstitute for Global Health Policy Research, Bureau of International Health Cooperation, National Center for Global Health and Medicine, Tokyo, Japan.
Yoko MutoInstitute for Global Health Policy Research, Bureau of International Health Cooperation, National Center for Global Health and Medicine, Tokyo, Japan.
Miyuki HoriInstitute for Global Health Policy Research, Bureau of International Health Cooperation, National Center for Global Health and Medicine, Tokyo, Japan.
Arisa IbaInstitute for Global Health Policy Research, Bureau of International Health Cooperation, National Center for Global Health and Medicine, Tokyo, Japan.
Hiroyasu IsoInstitute for Global Health Policy Research, Bureau of International Health Cooperation, National Center for Global Health and Medicine, Tokyo, Japan.
Hiroyasu IsoInstitute for Global Health Policy Research, Bureau of International Health Cooperation, National Center for Global Health and Medicine, Tokyo, Japan.
COVID-19 Recovery Study II Group

Funding

MHLW Research on Emerging and Re-emerging Infectious Diseases and Immunization JPMH21HA2011
6 · The paper itself

Abstract

Coronavirus disease-2019 (COVID-19) is associated with a wide range of post-acute sequelae. The prevalence of erectile dysfunction (ED) that developed after COVID-19 and the associated underlying factors were analyzed based on a questionnaire survey, COVID-19 Recovery Study II in Japan. A case-control study was conducted with those with or without ED one and two years hospitalized with COVID-19 between March and September 2021. Six hundred and nine Japanese men, with a median age of 48 years, were analyzed. During the study period, 116 subjects (19.0%) had erectile dysfunction. The patients with ED responded with less subjective awareness of recovery and high breathless and fatigue scores compared to those without ED. The patients with ED also showed higher Hospital Anxiety and Depression Scale-D (depression) and the EuroQol 5-dimensions 5-level scores for pain/discomfort and anxiety/depression scores compared before COVID-19 infection. Sleep disturbance was suggested to be associated with erectile dysfunction using an exploratory clustering analysis in the one-year survey. There were no associations of COVID-19 severity, reinfection, vaccination frequency, antiviral treatment for COVID-19 with the presence of erectile dysfunction. It was considered that mental support for the subject with erectile dysfunction as a long-COVID symptom is warranted.

Indexed as

COVID-19Erectile DysfunctionAdultAgedAnxietyCase-Control StudiesDepressionEast Asian PeopleHospitalizationHumansJapanMaleMiddle AgedPrevalenceSARS-CoV-2Surveys and QuestionnairesCoronavirus disease-2019 (COVID-19)COVID-19 Recovery Study II (CORES II)Erectile dysfunctionPost-acute sequelaeSleep disorder

Identifiers

PMID39979349
PMCPMC11842839

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.