ArticleNPJ Parkinson's disease2025
Subregion-specific associations of the basal forebrain with sleep and cognition in Parkinson's disease.
Article in NPJ Parkinson's disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- Altered Neurofluid Dynamics Markers in Middle-Aged and Older Women With Insomnia: A Multiparametric MR Neuroimaging Study.Journal of magnetic resonance imaging : JMRI · 2026Article
- Sleep-circadian modulation of autophagy and glymphatic function: failure of coordinated brain clearance in Parkinson's disease.NPJ Parkinson's disease · 2026Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
To elucidate the role of basal forebrain (BF) in non-motor symptoms of Parkinson's disease (PD), we investigated the association of sleep quality and cognition with BF volume and functional connectivity. The gray matter volume of the anterior intermediate part (Ch4ai) and the anterior lateral part (Ch4al) of the nucleus basalis Meynert were negatively associated with the PSQI global score. The posterior part of the nucleus basalis Meynert (Ch4p) volume was positively associated with visuospatial, memory, and executive functions. The PSQI global score correlated positively with functional connectivity from the Ch4al to the posterior cingulate, inferior parietal, anterior temporal, and medial prefrontal cortices, which correspond to the default mode network. Our results demonstrated that reduced volume of the anterior portion of the Ch4 and its aberrantly increased functional connectivity with the default mode network were closely related to poor overall sleep quality, while reduced volume of the posterior portion of the Ch4 was associated with decreased cognitive function in PD.
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Registered trials
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