Evidence map›Paper›PMID 39979280›Full record

ArticleNPJ science of food2025

Amylase/trypsin-inhibitor content and inhibitory activity of German common wheat landraces and modern varieties do not differ.

Nora Jahn, Sabrina Geisslitz, Ulla Konradl, Klaus Fleissner, Katharina A Scherf

Abstract read
In one paragraph

Article in NPJ science of food, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nora JahnDepartment of Bioactive and Functional Food Chemistry, Institute of Applied Biosciences, Karlsruhe Institute of Technology (KIT), Adenauerring 20 a, 76131, Karlsruhe, Germany.
Sabrina GeisslitzLeibniz Institute for Food Systems Biology at the Technical University of Munich, Lise-Meitner-Str. 34, 85354, Freising, Germany.
Ulla KonradlBavarian State Research Center for Agriculture (LfL), Kleeberg 14, 94099, Ruhstorf an der Rott, Germany.
Klaus FleissnerBavarian State Research Center for Agriculture (LfL), Kleeberg 14, 94099, Ruhstorf an der Rott, Germany.
Katharina A ScherfDepartment of Bioactive and Functional Food Chemistry, Institute of Applied Biosciences, Karlsruhe Institute of Technology (KIT), Adenauerring 20 a, 76131, Karlsruhe, Germany. k.scherf.leibniz-lsb@tum.de.

Funding

Deutsche Forschungsgemeinschaft 445432254Federal Ministry of Food and Agriculture 2819OE021
6 · The paper itself

Abstract

Amylase/trypsin-inhibitors (ATIs) are triggers for wheat-related disorders like baker's asthma and non-celiac wheat sensitivity. With the rise of wheat-related disorders among the population, the hypothesis that breeding may have resulted in changes in the protein composition of wheat was put forward. The ATI content of 14 German common wheat landraces and six modern varieties harvested in three consecutive years was analyzed by liquid chromatography-tandem mass spectrometry, and the inhibitory activity against α-amylase was measured with an enzymatic assay. The mean ATI content and proportion of crude protein of both groups did not differ. There were also only small differences in the content and proportion of single ATIs. The mean values for the inhibitory activity of both groups were also similar. These results indicate that breeding might not have led to changes in the protein composition and landraces are unlikely to be better tolerated than modern varieties.

Identifiers

PMID39979280
PMCPMC11842761

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.