Evidence map›Paper›PMID 39979193›Full record

ReviewTrends in parasitology2025

The impact of blood on vector-borne diseases with emphasis on mosquitoes and sand flies.

Pedro Cecilio, Eva Iniguez, Patrick Huffcutt, Servio P Ribeiro, Shaden Kamhawi, Jesus G Valenzuela, Tiago D Serafim

Abstract readReview
In one paragraph

Review in Trends in parasitology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Leishmaniasis: Vector-Host-Pathogen Interactions in Health and Disease.Tropical medicine and infectious disease · 2025
    Article
  5. Article
  6. Review
  7. Frontiers in immunology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pedro CecilioVector Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA.
Eva IniguezVector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA.
Patrick HuffcuttVector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA.
Servio P RibeiroLaboratory of Ecology of Diseases & Forests, NUPEB/ICEB, Federal University of Ouro Preto, Ouro Preto, Brazil.
Shaden KamhawiVector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA. Electronic address: skamhawi@niaid.nih.gov.
Jesus G ValenzuelaVector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA. Electronic address: jvalenzuela@niaid.nih.gov.
Tiago D SerafimVector Molecular Biology Section, Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20852, USA. Electronic address: tiago.donatelliserafim@nih.gov.

Funding

Molecular approaches to understand vector-host and vector-pathogen interactionsZ01AI000932 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI VALENZUELA, JESUS · 2003 to 2008
$1.9M
Intramural NIH HHS Z01 AI000932
6 · The paper itself

Abstract

The impact of blood and its factors on vector-borne diseases is significant and multifaceted yet understudied. While blood is expected to play a central role in transmission, pathogen development, vector behavior, and vector competence, in experimental settings, most studies are developed in the frame of a single, infected blood meal. To effectively combat vector-borne diseases, we need to determine what is the influence of insect blood-feeding behavior on transmission and development of pathogens, toward translation to natural field settings. This review summarizes current findings, highlights key gaps, and outlines future research directions to enhance our understanding of the role of blood in vector-borne disease transmission.

Indexed as

BloodCulicidaeInsect VectorsMosquito VectorsPsychodidaeVector Borne DiseasesAnimalsFeeding BehaviorHumansbloodmultiple blood mealstranslational researchvector behaviorvector-borne diseasesvector competence

Identifiers

PMID39979193
PMCPMC11998667

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.