Evidence map›Paper›PMID 39979015›Full record

ArticleBiomolecules & therapeutics2025

Quercetin-3-Methyl Ether Induces Early Apoptosis to Overcome HRV1B Immune Evasion, Suppress Viral Replication, and Mitigate Inflammatory Pathogenesis.

Jae-Hyoung Song, Seo-Hyeon Mun, Sunil Mishra, Seong-Ryeol Kim, Heejung Yang, Sun Shim Choi, Min-Jung Kim, Dong-Yeop Kim, Sungchan Cho, Youngwook Ham and 5 more

Abstract read
In one paragraph

Article in Biomolecules & therapeutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jae-Hyoung SongDepartment of Pharmacy, Kangwon National University, Chuncheon 24341, Republic of Korea.
Seo-Hyeon MunDepartment of Pharmacy, Kangwon National University, Chuncheon 24341, Republic of Korea.
Sunil MishraCollege of Pharmacy, Yeungnam University, Gyeongsan 38541, Republic of Korea.
Seong-Ryeol KimDivision of Acute Viral Diseases, Centers for Emerging Virus Research, National Institute of Health, Korea Disease Control and Prevention Agency, Cheongju 28159, Republic of Korea.
Heejung YangDepartment of Pharmacy, Kangwon National University, Chuncheon 24341, Republic of Korea.
Sun Shim ChoiDivision of Biomedical Convergence, College of Biomedical Science, Institue od Bioscience & Biotechnology, Kangwon National University, Chuncheon 24341, Republic of Korea.
Min-Jung KimDepartment of Pharmacy, Kangwon National University, Chuncheon 24341, Republic of Korea.
Dong-Yeop KimDivision of Biomedical Convergence, College of Biomedical Science, Institue od Bioscience & Biotechnology, Kangwon National University, Chuncheon 24341, Republic of Korea.
Sungchan ChoNucleic Acid Therapeutics Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju 28116, Republic of Korea.
Youngwook HamNucleic Acid Therapeutics Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Cheongju 28116, Republic of Korea.
Hwa-Jung ChoiDepartment of Beauty Art, Youngsan University, 142 Bansong Beltway, Busan 48015, Republic of Korea.
Won-Jin BaekDepartment of Beauty Art, Youngsan University, 142 Bansong Beltway, Busan 48015, Republic of Korea.
Yong Soo KwonDepartment of Pharmacy, Kangwon National University, Chuncheon 24341, Republic of Korea.
Jae-Hoon ChangCollege of Pharmacy, Yeungnam University, Gyeongsan 38541, Republic of Korea.
Hyun-Jeong KoDepartment of Pharmacy, Kangwon National University, Chuncheon 24341, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human rhinovirus (HRV) causes the common cold and exacerbates chronic respiratory diseases, such as asthma and chronic obstructive pulmonary disease. Despite its significant impact on public health, there are currently no approved vaccines or antiviral treatments for HRV infection. Apoptosis is the process through which cells eliminate themselves through the systematic activation of intrinsic death pathways in response to various stimuli. It plays an important role in viral infections and serves as a key immune defense mechanism in the interactions between viruses and the host. In the present study, we investigated the antiviral effects of quercetin-3-methyl ether, a flavonoid isolated from

Indexed as

AntiviralApoptosisFlavonoidHuman rhinovirusQuercetin-3-methyl ether

Identifiers

PMID39979015
PMCPMC11893485

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.