ArticleBJGP open2025
Sex differences in the prescription of antihypertensive medications in primary care patients: an observational study.
Article in BJGP open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Preventive Cardiovascular Medication Prescribing Patterns in Menopausal Women.Mayo Clinic proceedings. Innovations, quality & outcomes · 2026Article
- Long-Term Persistence and Treatment Changes of Antihypertensive Therapy: A 5-Year Cohort Study.Basic & clinical pharmacology & toxicology · 2026Article
- Review
- Article
- Women's heart disease research in the netherlands: angina with non-obstructive coronary artery disease and beyond.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2025Review
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPharmacological prescription guidelines for hypertension lack differentiation between the sexes, despite reported sex differences in prevalence, awareness, pathophysiology, and pharmacological response.
aimTo assess prescription patterns of blood pressure-lowering medication among females and males in primary care. DESIGN &
settingIn this observational study, which was undertaken in the Netherlands, we analysed data collected in 2018 during routine primary care practice among those pharmacologically treated for elevated blood pressure, and free from cardiovascular comorbidities or diabetes mellitus.
methodWe assessed sex differences in the number of prescribed drugs, defined daily dosage, type of antihypertensive medication, and blood pressure control. We adjusted for differences between sexes in age and other covariates.
resultsThis study included 8596 females and 5788 males. Both females and males were prescribed on average 1.8 antihypertensive agents per person. Females compared with males were prescribed a significantly lower defined daily dosage (1.8 versus 2.1,
conclusionIn those pharmacologically treated for elevated blood pressure, differences between females and males exist in defined daily dosage, type of antihypertensive medication, and blood pressure control, with females achieving better hypertension control than males with different type of medication and lower dosage.
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