Evidence map›Paper›PMID 39978816›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2025

Theranostics for Neuroblastoma: Making Molecular Radiotherapy Work Better.

Peter J Gawne, Helen E Bryant, Steven G DuBois, Sally L George, Juliet Gray, Leona Knox, Kyle B Matchett, Connie Peet, Katherine A Vallis, Hugh J Wallace and 2 more

Abstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Fraction-dependent dose dynamics and clinical safety in high-risk neuroblastoma treated with [European journal of nuclear medicine and molecular imaging · 2026
    Trial
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Peter J GawneCentre for Cancer Biomarkers and Biotherapeutics, Barts Cancer Institute, Queen Mary, University of London, London, United Kingdom.
Helen E BryantSchool of Medicine and Population Health, University of Sheffield, Sheffield, United Kingdom.
Steven G DuBoisDana-Farber/Boston Children's Cancer and Blood Disorders Center, Harvard Medical School, Boston, Massachusetts.
Sally L GeorgeDivision of Clinical Studies, Institute of Cancer Research, London, United Kingdom.
Juliet GrayCentre for Cancer Immunology, University of Southampton, Southampton, United Kingdom.
Leona KnoxSolving Kids' Cancer, London, United Kingdom.
Kyle B MatchettPersonalised Medicine Centre and Clinical Translational Research and Innovation Centre, Altnagelvin Area Hospital, School of Medicine, Ulster University, Derry-Londonderry, United Kingdom.
Connie PeetDepartment of Radiotherapy, University College London Hospitals NHS Foundation Trust, London, United Kingdom.
Katherine A VallisDepartment of Oncology, University of Oxford, Oxford, United Kingdom.
Hugh J WallacePaediatric Nuclear Medicine, Royal Hospital for Children, Glasgow, United Kingdom.
Simon WanInstitute of Nuclear Medicine, University College London Hospitals NHS Foundation Trust/University College London, London, United Kingdom; and.
Mark N GazeDepartment of Oncology, University College London Hospitals NHS Foundation Trust, London, United Kingdom mgaze@nhs.netmark.gaze@ucl.ac.uk.

Funding

Cancer Research UK C7893/A28990
6 · The paper itself

Abstract

Despite improvements in neuroblastoma treatment, survival figures lag behind those of many other childhood malignancies. New treatments, and better use of existing treatments, are essential to reduce mortality. Neuroblastoma expresses several molecular targets for radionuclide imaging and therapy, of which the most widely exploited is the norepinephrine transporter. [

Indexed as

NeuroblastomaTheranostic Nanomedicine3-IodobenzylguanidineHumans3-Iodobenzylguanidinemolecular radiotherapyneuroblastomaradionuclide therapyradiopharmaceutical therapytheranostics

Identifiers

PMID39978816
PMCPMC11960609

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.