Evidence map›Paper›PMID 39978322›Full record

ArticleGynecologic and obstetric investigation2025

The Role of Artificial Intelligence in Gynecologic Oncology Decision-Making: A Feasibility Study.

Iason Psilopatis, Iason Psilopatis, Nadezda Sipulina, Frederik A Stuebs, Felix Heindl, Patrik Poeschke, Simon Bader, Annika Krueckel, Peter A Fasching, Matthias W Beckmann and 1 more

Abstract read
In one paragraph

Article in Gynecologic and obstetric investigation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Iason Psilopatis
Iason PsilopatisDepartment of Gynecology and Obstetrics, Universitätsspital Basel, University of Basel, Basel, Switzerland.
Nadezda SipulinaDepartment of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Frederik A StuebsDepartment of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Felix HeindlDepartment of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Patrik PoeschkeDepartment of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Simon BaderDepartment of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Annika KrueckelDepartment of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Peter A FaschingDepartment of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Matthias W BeckmannDepartment of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Julius EmonsDepartment of Gynecology and Obstetrics, Comprehensive Cancer Center Erlangen-EMN (CCC ER-EMN), Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe objective of this study was to examine the potential of artificial intelligence (AI) in gynecologic oncology decision-making.

designA feasibility study was conducted.

participantsFictitious case vignettes of patients with gynecologic carcinomas were used.

settingThe setting was a fictive one.

methodsFictitious case vignettes of gynecologic carcinomas were created and evaluated by physicians with varying levels of professional experience, as well as by language models including ChatGPT 4.0, Google Gemini, and Bing Copilot. Treatment approval decisions were based on standardized clinical and laboratory criteria.

resultsTwo cases of breast cancer, 1 case of ovarian cancer, 1 case of cervical cancer, and 1 case of endometrial cancer were evaluated. All three language models were able to evaluate all clinical cases and make therapy-relevant suggestions, with ChatGPT providing the most clear and concise recommendations that were in 3 cases totally consistent with physician assessments. LIMITATIONS: This study was limited to a feasibility study based on five fictitious case vignettes.

conclusionsThe study demonstrates that AI models, such as ChatGPT, can to some extent evaluate clinical cases, recognize clinical and/or laboratory abnormalities, and make therapy-related suggestions. Despite high overall agreement, differences were predominantly noted in the more complex cases, rendering human interpretation necessary. The findings underscore the benefits of AI in terms of clarity, time efficiency, and cost-effectiveness. Future research should further explore the application of AI to real patient data and development of hybrid decision models to optimize integration into clinical practice.

Indexed as

Artificial IntelligenceClinical Decision-MakingGenital Neoplasms, FemaleMedical OncologyDecision MakingFeasibility StudiesFemaleGynecologyHumansArtificial intelligenceDecision-makingGynecologic oncology

Identifiers

PMID39978322
PMCPMC12500289

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.