Evidence map›Paper›PMID 39978291›Full record

ArticleDevelopmental cognitive neuroscience2025

Infant attention and frontal EEG neuromarkers of childhood ADHD.

Cassondra M Eng, Leslie A Patton, Martha Ann Bell

Abstract read
In one paragraph

Article in Developmental cognitive neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Patterns of Early Development in Children with ADHD.Journal of clinical child and adolescent psychology : the official journal for the Society of Clinical Child and Adolescent Psychology, American Psychological Association, Division 53 · 2026
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Cassondra M EngDepartment of Psychiatry & Behavioral Sciences, Stanford University, Center for Interdisciplinary Brain Sciences Research, 1520 Page Mill Road, Stanford, CA 94304, USA; Department of Psychology, Virginia Tech, 890 Drillfield Drive, Blacksburg, VA 24060, USA. Electronic address: cassie24@stanford.edu.
Leslie A PattonDepartment of Psychology, Virginia Tech, 890 Drillfield Drive, Blacksburg, VA 24060, USA.
Martha Ann BellDepartment of Psychology, Virginia Tech, 890 Drillfield Drive, Blacksburg, VA 24060, USA.

Funding

VT Post Baccalaureate Research and Education ProgramR25GM066534 · NIGMS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI SMITH, EDWARD J · 2003 to 2024
$7.6M
TRAINING FOR CHILD PSYCHIATRY AND CHILD DEVELOPMENTT32MH019908 · NIMH · STANFORD UNIVERSITY · PI IAN H GOTLIB, DAVID S HONG · 1993 to 2026
$6.3M
Psychobiology of Cognitive DevelopmentR01HD049878 · NICHD · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI BELL, MARTHA ANN · 2007 to 2017
$5.0M
Modified Use of E-cigarettes and Marketing on YouTubeR01DA049878 · NIDA · YALE UNIVERSITY · PI KONG, GRACE · 2020 to 2022
$1.4M
Infant Temperament and Cognitive DevelopmentR03HD043057 · NICHD · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI BELL, MARTHA ANN · 2003 to 2004
$141k
NICHD NIH HHS R01 HD049878NICHD NIH HHS R03 HD043057NIDA NIH HHS R01 DA049878NIGMS NIH HHS R25 GM066534NIMH NIH HHS T32 MH019908
6 · The paper itself

Abstract

Numerous electroencephalogram (EEG) studies have sought to elucidate the neural mechanisms of attention deficit hyperactivity disorder (ADHD), with most of the existing literature focused on children, adolescents, and adults. In this retrospective study, measures of frontal EEG power and behavioral attention of 40 5-month-old infants later diagnosed with ADHD in childhood were compared to 40 systematically matched-control infants. Compared to the control group, infants in the ADHD group exhibited longer looking fixations during an attention task. Frontal EEG power in the 6-9 Hz infant alpha band was lower in the ADHD group compared to the control group. Mean frontal EEG power was associated with visual fixations, underscoring specific attention behavior corresponding to frontal brain development in infancy. Infants later diagnosed with ADHD exhibited higher attention problems in childhood at ages 4 and 9 compared to the control group, and longer looking fixations in infancy were associated with higher childhood ADHD-related symptomatology. These findings suggest that decreased infant frontal EEG power and looking fixations as early as 5-months of age may serve as important early markers of later ADHD and can aid in building a more comprehensive model of ADHD from a developmental neuroscience approach.

Indexed as

AttentionAttention Deficit Disorder with HyperactivityFrontal LobeChildChild, PreschoolElectroencephalographyFemaleFixation, OcularHumansInfantMaleRetrospective StudiesADHDAttentionChildhoodEEGFrontal lobeInfancy

Identifiers

PMID39978291
PMCPMC11889623

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.