Evidence map›Paper›PMID 39977950›Full record

ArticleBioconjugate chemistry2025

Conditional Control of Benzylguanine Reaction with the Self-Labeling SNAP-tag Protein.

Steven E Caldwell, Isabella R Demyan, Gianna N Falcone, Avani Parikh, Jason Lohmueller, Alexander Deiters

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioconjugate chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Steven E CaldwellDepartment of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.
Isabella R DemyanDepartment of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.
Gianna N FalconeDepartment of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.
Avani ParikhDepartment of Surgery, Division of Surgical Oncology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, United States.ORCID 0000-0002-4083-0987
Jason LohmuellerDepartment of Surgery, Division of Surgical Oncology, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, United States.
Alexander DeitersDepartment of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.ORCID 0000-0003-0234-9209

Funding

VECTOR CORE FACILITYP30CA047904 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CHRISTOPHER J. BAKKENIST · 1988 to 2026
$158.0M
Conditional control of universal antigen receptor signalingR01GM142007 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LOHMUELLER, JASON JAKOB · 2021 to 2025
$2.2M
Special BD LSRFortessaTMS10OD011925 · OD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BORGHESI, LISA · 2012 to 2012
$383k
NCI NIH HHS P30 CA047904NIGMS NIH HHS R01 GM142007NIH HHS S10 OD011925
6 · The paper itself

Abstract

SNAP-tag, a mutant of the O

Indexed as

GuanineO(6)-Methylguanine-DNA MethyltransferaseHumansGuanineO(6)-benzylguanineO(6)-Methylguanine-DNA Methyltransferase

Identifiers

PMID39977950
PMCPMC11926790

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.