ArticleScience (New York, N.Y.)2025
Reviving-like prosocial behavior in response to unconscious or dead conspecifics in rodents.
Article in Science (New York, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed.
- Hypothalamic-amygdala gating of caregiving-like prosocial behavior in mice.The Journal of clinical investigation · 2026Article
- The MPOA-VTA Pathway: From Pup Care to Adult Helping.Neuroscience bulletin · 2026Article
- Adolescent Social Isolation Induces Persistent Impairments in Emotional Discrimination and Helping Behavior.eNeuro · 2026Article
- Experience-dependent modulation of prosocial touch in mice.iScience · 2026Article
- The neural control of infanticide and parental behaviors in male mice.bioRxiv : the preprint server for biology · 2026Article
- Neural correlates of adversity-overcoming pup rescue behavior in female mice.Scientific reports · 2026Article
- The Anterior Cingulate Cortex and Prosocial Behavior toward Others in Negative State.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Review
- Experience-dependent maturation of somatosensory parvalbumin interneurons during social development in prairie voles.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Heightened empathic responses led by imbalanced cortico-amygdala circuit inbioRxiv : the preprint server for biology · 2025Article
- Stranger-directed consolation-like behavior in mice in a test of social decision making.Hormones and behavior · 2025Article
- Through Human Eyes: Owner Insights into the Social Relationships of Pet Rats.Animals : an open access journal from MDPI · 2025Article
- Causes of symptoms and symptom persistence in long COVID and myalgic encephalomyelitis/chronic fatigue syndrome.Cell reports. Medicine · 2025Review
- Brain circuits that regulate social behavior.Molecular psychiatry · 2025Review
- Interpreting mouse's intention from analysis of prosocial behavior.Lab animal · 2025Article
- Distinct oxytocin signaling pathways synergistically mediate rescue-like behavior in mice.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- The paraventricular nucleus of the hypothalamus: a key node in the control of behavioural states.The Journal of physiology · 2025Review
- A neural basis for prosocial behavior toward unresponsive individuals.Science (New York, N.Y.) · 2025Article
- Reviving-like prosocial behavior in response to unconscious or dead conspecifics in rodents.Science (New York, N.Y.) · 2025Article
- Most prominent challenges in translational neuroscience and strategic solutions to bridge the gaps: Perspectives from an editorial board interrogation.Exploration of neuroscience · 2025Article
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7 authors.
Funding
Abstract
Whereas humans exhibit emergency responses to assist unconscious individuals, how nonhuman animals react to unresponsive conspecifics is less well understood. We report that mice exhibit stereotypic behaviors toward unconscious or dead social partners, which escalate from sniffing and grooming to more forceful actions such as mouth or tongue biting and tongue pulling. The latter intense actions, more prominent in familiar pairs, begin after prolonged immobility and unresponsiveness and cease when the partner regains activity. Their consequences, including improved airway opening and clearance and accelerated recovery from unconsciousness, suggest rescue-like efforts. Oxytocin neurons in the hypothalamic paraventricular nucleus respond differentially to the presence of unconscious versus active partners, and their activation, along with oxytocin signaling, is required for the reviving-like actions. This tendency to assist unresponsive members may enhance group cohesion and survival of social species.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.