Evidence map›Paper›PMID 39977301›Full record

ArticleMolecular microbiology2025

Future Directions of the Prokaryotic Chromosome Field.

E A Abbondanzieri, A B Badrinarayanan, D Barillà, S D Bell, F Blombach, J Y Bouet, S Bulgheresi, Q A D Cao, R T Dame, C Dekker and 40 more

Abstract readEditorial
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

50 authors.

E A AbbondanzieriDepartment of Biology, University of Rochester, Rochester, New York, USA.
A B BadrinarayananNCBS, Bengaluru, India.
D BarillàDepartment of Biology, University of York, York, UK.
S D BellIndiana University, Bloomington, Indiana, USA.
F BlombachUniversity College, London, UK.ORCID 0000-0001-5337-8662
J Y BouetLMGM-CBI, CNRS, University of Toulouse Paul Sabatier, Toulouse, France.ORCID 0000-0003-1488-5455
S BulgheresiDepartment of Functional and Evolutionary Ecology, Environmental Cell Biology Group, University of Vienna, Vienna, Austria.
Q A D CaoChinese Academy of Sciences, Shenzhen Institutes of Advanced Technology, Shenzhen, China.
R T DameLeiden Institute of Chemistry, Leiden University, Leiden, the Netherlands.ORCID 0000-0001-9863-1692
C DekkerKavli Institute of Nanoscience Delft, Delft, the Netherlands.
M DemuysereMolecular Microbiology and Structural Biochemistry, CNRS/University of Lyon 1, Lyon, France.
O EspéliCollége de France, Paris, France.
P C M FoggUniversity of York, York, UK.ORCID 0000-0001-5324-4293
P L FreddolinoUniversity of Michigan, Ann Arbor, Michigan, USA.
M GanjiIndian Institute of Science, Bangalore, India.
T M GersonUniversity of Nevada-Las Vegas, Las Vegas, Nevada, USA.
D C GraingerUniversity of Birmingham, Birmingham, UK.ORCID 0000-0003-3375-5154
L W HamoenUniversity of Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0001-9251-1403
J HarjuVrije Universiteit Amsterdam, Amsterdam, the Netherlands.ORCID 0000-0001-9696-5453
A HocherMedical Research Council London Institute of Medical Sciences, London, UK.
C M HustmyerDepartment of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-9144-3872
J K Kaljevicde Duve Institute, UCLouvain, Brussels, Brussels, Belgium.
M K KarneyUniversity of Nevada-Las Vegas, Las Vegas, Nevada, USA.
N KlecknerHarvard University, Cambridge, Massachusetts, USA.
G Lalouxde Duve Institute, UCLouvain, Brussels, Brussels, Belgium.
R LandickDepartment of Biochemistry, University of Wisconsin-Madison, Madison, Wisconsin, USA.
V S LioyCEA, CNRS, Institute for Integrative Biology of the Cell (I2BC), Université Paris-Saclay, France.ORCID 0000-0002-5366-0462
W L LiuChinese Academy of Sciences, Shenzhen Institutes of Advanced Technology, Shenzhen, China.
C L LiuChinese Academy of Sciences, China.
J MäkeläInstitute of Biotechnology, University of Helsinki, Helsinki, Finland.
A S MeyerDepartment of Biology, University of Rochester, Rochester, New York, USA.ORCID 0000-0002-4164-0122
A NoyUniversity of York, York, UK.
M P PineauMicrobiology, Adaptation and Pathogenesis, UMR5240, INSA, Lyon, France.
K PremrajkaUniversity of Kiel, Kiel, Germany.
L R RackiUniversity of Kiel, USA.ORCID 0000-0003-2209-7301
F-Z M RashidLeiden University, Leiden, the Netherlands.
K SchnetzInstitute for Genetics, University of Cologne, Cologne, Germany.ORCID 0000-0003-4693-6202
S SchwabLeiden University, Leiden, the Netherlands.
M TišmaKavli Institute of Nanoscience Delft, Delft, the Netherlands.
A I van der SijsUniversiteit Utrecht, Utrecht, the Netherlands.
T van HeeschVan't Hoff Institute for Molecular Sciences, University of Amsterdam, the Netherlands.
R van Raaphorstde Duve Institute, UCLouvain, Brussels, Brussels, Belgium.
J VreedeVan't Hoff Institute for Molecular Sciences, University of Amsterdam, the Netherlands.
A W WalkerDepartment of Biology, University of Rochester, Rochester, New York, USA.
J-C WalterLaboratory Charles Coulomb (L2C), CNRS & Montpellier Université, Montpellier, France.
S C WeberDepartment of Biology, McGill University, Montreal, Quebec, Canada.
P A WigginsUniversity of Washington, Seattle, Washington, USA.
H J WingUniversity of Nevada-Las Vegas, Las Vegas, Nevada, USA.ORCID 0000-0003-0123-5568
J XiaoJohns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Z ZhangChinese Academy of Sciences, Shenzhen Institutes of Advanced Technology, Shenzhen, China.

Funding

STRUCTURE/FUNCTION OF TRANSCRIPTION COMPLEX RNA HAIRPINSR01GM038660 · NIGMS · WASHINGTON UNIVERSITY · PI Robert Landick · 1992 to 2026
$12.2M
Understanding transcriptional silencing & anti-silencing mechanisms in ShigellaR15AI090573 · NIAID · UNIVERSITY OF NEVADA LAS VEGAS · PI WING, HELEN J · 2010 to 2024
$2.3M
NIAID NIH HHS R15 AI090573NIGMS NIH HHS R01 GM038660The Lorentz Center is funded by the Dutch Research Council (NWO) and Leiden University
6 · The paper itself

Abstract

In September 2023, the Biology and Physics of Prokaryotic Chromosomes meeting ran at the Lorentz Center in Leiden, The Netherlands. As part of the workshop, those in attendance developed a series of discussion points centered around current challenges for the field, how these might be addressed, and how the field is likely to develop over the next 10 years. The Lorentz Center staff facilitated these discussions via tools aimed at optimizing productive interactions. This Perspective article is a summary of these discussions and reflects the state-of-the-art of the field. It is expected to be of help to colleagues in advancing their own research related to prokaryotic chromosomes and inspiring novel interdisciplinary collaborations. This forward-looking perspective highlights the open questions driving current research and builds on the impressive recent progress in these areas as represented by the accompanying reviews, perspectives, and research articles in this issue. These articles underline the multi-disciplinary nature of the field, the multiple length scales at which chromatin is studied in vitro and in and highlight the differences and similarities of bacterial and archaeal chromatin and chromatin-associated processes.

Indexed as

ArchaeaBacteriaChromosomes, ArchaealChromosomes, BacterialChromatinChromatinarchaeal chromatinarchaeal chromosomebacterial chromatinbacterial chromosomenucleoid

Identifiers

PMID39977301
PMCPMC12720490

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.