Evidence map›Paper›PMID 39977243›Full record

ArticleJournal of natural products2025

Menominin A and B: Cytotoxic Cyclodepsipeptides from the Freshwater Sponge-Associated Cyanobacterium

Lydia J Davis, Aleksej Krunić, Kelsey Alexander, Manead Khin, Jared S Wood, Cody Earp, Manuel Rangel-Grimaldo, Alessandra S Eustáquio, Joanna E Burdette, R Thomas Williamson and 2 more

Abstract read
In one paragraph

Article in Journal of natural products, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lydia J DavisDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Illinois Chicago, Chicago, Illinois 60612, United States.ORCID 0000-0002-0898-7191
Aleksej KrunićDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Illinois Chicago, Chicago, Illinois 60612, United States.
Kelsey AlexanderDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Illinois Chicago, Chicago, Illinois 60612, United States.ORCID 0000-0002-4727-5349
Manead KhinDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Illinois Chicago, Chicago, Illinois 60612, United States.ORCID 0000-0002-5744-9584
Jared S WoodDepartment of Chemistry and Biochemistry, University of North Carolina Wilmington, Wilmington, North Carolina 28409, United States.ORCID 0000-0002-3940-0461
Cody EarpDepartment of Chemistry and Biochemistry, University of North Carolina Greensboro, Greensboro, North Carolina 27412, United States.
Manuel Rangel-GrimaldoDepartment of Chemistry and Biochemistry, University of North Carolina Greensboro, Greensboro, North Carolina 27412, United States.
Alessandra S EustáquioDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Illinois Chicago, Chicago, Illinois 60612, United States.ORCID 0000-0002-7852-7844
Joanna E BurdetteDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Illinois Chicago, Chicago, Illinois 60612, United States.ORCID 0000-0002-7271-6847
R Thomas WilliamsonDepartment of Chemistry and Biochemistry, University of North Carolina Wilmington, Wilmington, North Carolina 28409, United States.ORCID 0000-0001-7450-3135
Nicholas H OberliesDepartment of Chemistry and Biochemistry, University of North Carolina Greensboro, Greensboro, North Carolina 27412, United States.
Jimmy OrjalaDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Illinois Chicago, Chicago, Illinois 60612, United States.ORCID 0000-0002-4420-2048

Funding

Project 3:Isolation Chemistry of Filamentous Fungi and Biological EvaluationP01CA125066 · NCI · OHIO STATE UNIVERSITY · PI Joanna E Burdette · 2007 to 2026
$27.2M
Research Training in Natural Product Complementary and Integrative HealthT32AT007533 · NCCIH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI Joanna E Burdette, JIMMY ORJALA · 2013 to 2026
$4.3M
IRACDA at University of Illinois at ChicagoK12GM139186 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI BURDETTE, JOANNA E, NONN, LARISA · 2020 to 2024
$3.6M
NCCIH NIH HHS T32 AT007533NCI NIH HHS P01 CA125066NIGMS NIH HHS K12 GM139186
6 · The paper itself

Abstract

Menominin A (

Indexed as

Antineoplastic AgentsDepsipeptidesDrug Screening Assays, AntitumorNostocPoriferaAnimalsFemaleFresh WaterHumansMolecular StructureMultigene FamilyNuclear Magnetic Resonance, BiomolecularAntineoplastic AgentsDepsipeptides

Identifiers

PMID39977243
PMCPMC11952978

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.