ArticleNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2025
Pectoralis major muscle index as an opportunistic predictor of mortality in acute stroke patients treated with intravenous thrombolysis.
Article in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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2 citing papers in PubMed.
- Association of pectoralis major muscle cross-sectional area and mean density on chest CT with mortality in elderly COVID-19 patients: sex and side differences.BMC pulmonary medicine · 2026Article
- The pectoralis major index: a novel computed tomography biomarker for low thoracic muscle mass and eastern cooperative oncology group performance status in lung cancer patients.Frontiers in nutrition · 2026Article
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Abstract
backgroundPremorbid sarcopenia in acute stroke indicates poor prognosis. Since formal sarcopenia tests cannot be performed, the muscle features imaged in diagnostic studies are opportunistically used as surrogates for sarcopenia in the acute period.
methodsIn 110 consecutive acute ischemic anterior circulation stroke patients treated with intravenous tissue plasminogen activator alone (mean age: 73±13 years, 55% women), the cross-sectional area (CSA) and attenuation of pectoralis major and minor muscles and mediastinal adipose tissue were measured at admission computed tomography (CT) angiography source images.
resultsPectoralis major and minor muscle CSA (mm
conclusionsOur retrospective analysis documents that the pectoralis major index, a readily available CT anthropometry surrogate for sarcopenia, is an independent predictor of survival in patients with acute ischemic stroke undergoing systemic thrombolysis. It may suggest that the pectoralis major index could be included in the prognostic toolkit of acute ischemic stroke.
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