Evidence map›Paper›PMID 39976853›Full record

ReviewHeart failure reviews2025

Worsening heart failure: progress, pitfalls, and perspectives.

Cândida Fonseca, Rui Baptista, Fátima Franco, Brenda Moura, Joana Pimenta, Pedro Moraes Sarmento, José Silva Cardoso, Dulce Brito

Erratum issuedAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Heart failure reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Cândida FonsecaHeart Failure Clinic, Hospital S. Francisco Xavier, Unidade Local de Saúde Lisboa Ocidental, Lisbon, Portugal. mcandidafonseca@gmail.com.
Rui BaptistaCardiology Department, Unidade Local de Saúde de Entre Douro E Vouga, Santa Maria da Feira, Portugal.
Fátima FrancoAdvanced Heart Failure Unit, Cardiology Department, Unidade Local de Saúde Coimbra, Coimbra, Portugal.
Brenda MouraHospital das Forças Armadas, Porto Campus, Porto, Portugal.
Joana PimentaInternal Medicine Department, Hospital Eduardo Santos Silva, Unidade Local de Saúde Gaia e Espinho, Vila Nova de Gaia, Portugal.
Pedro Moraes SarmentoHeart Failure Clinic, Hospital da Luz, Lisbon, Portugal.
José Silva CardosoDepartment of Cardiology, Unidade Local de Saúde São João, Porto, Portugal.
Dulce BritoDepartment of Cardiology, Unidade Local de Saúde Santa Maria, Lisboa, Portugal.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

For most patients with chronic heart failure (HF), the clinical course of the disease includes periods of apparent clinical stability punctuated by episodes of clinical deterioration with worsening signs and symptoms, a condition referred to as worsening heart failure (WHF). Over time, episodes of WHF may become more frequent, and patients may enter a cycle of recurrent events associated with deterioration in their quality of life and functional capacity, hospitalizations, and ultimately death. WHF is apparently an old concept but seems to have acquired new boundaries in terms of definition and clinical and prognostic value due to the fast-paced evolution of the HF treatment landscape and the emergence of new drugs in this setting. As a result, the management of WHF is being reshaped. In the present paper, a group of HF experts gathered to discuss the concept, prevention, detection, and treatment of WHF.

Indexed as

Disease ManagementHeart FailureClinical DeteriorationDisease ProgressionHumansPrognosisQuality of LifeChronic heart failureEmerging treatmentExpert consensusGuideline-directed medical therapyManagementVericiguatWorsening heart failure

Identifiers

PMID39976853
PMCPMC12165898

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.