Evidence map›Paper›PMID 39976815›Full record

ReviewDrugs & aging2025

Unveiling Cognitive Impairment in Older Adults with Cancer on Systemic Anticancer Therapy: A Comprehensive Review.

Raquel Paramo Fernandez, Gemma Fargas Baella, Vanya Slavova-Boneva, Nicolò Matteo Luca Battisti

Abstract readReview
PubMed Publisher
In one paragraph

Review in Drugs & aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Raquel Paramo FernandezDepartment of Geriatrics, Getafe University Hospital, Madrid, Spain.ORCID 0009-0005-3394-7692
Gemma Fargas BaellaDepartment of Geriatrics, Vic University Hospital, Barcelona, Spain.ORCID 0009-0009-8451-9013
Vanya Slavova-BonevaDepartment of Medicine, Breast Unit and Senior Adult Oncology Program, The Royal Marsden NHS Foundation Trust, Downs Road, Sutton, London, SM2 5PT, UK.ORCID 0009-0004-5415-0300
Nicolò Matteo Luca BattistiDepartment of Medicine, Breast Unit and Senior Adult Oncology Program, The Royal Marsden NHS Foundation Trust, Downs Road, Sutton, London, SM2 5PT, UK. nicolo.battisti@rmh.nhs.uk.ORCID 0000-0002-1063-1717

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer-related cognitive impairment significantly affects cancer management and decision-making. While the exact mechanisms underlying cancer-related cognitive dysfunction remain complex and multifaceted, different factors have been identified that may help predict which patients are at increased risk for cognitive decline. In this article, we provide a comprehensive overview of systemic cancer therapy-induced cognitive impairment in older adults, including signs and symptoms, diagnosis, and management. In addition, we discuss the evidence available on the impact of endocrine therapy, cytotoxic chemotherapy, immunotherapy and targeted agents on cognition in this population.

Indexed as

Antineoplastic AgentsChemotherapy-Related Cognitive ImpairmentCognitive DysfunctionNeoplasmsAgedHumansImmunotherapyAntineoplastic Agents

Identifiers

PMID39976815

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.